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Articles Related to iNOS

Optimization of Pseudomonas aeruginosa for Chlorpyrifos Degradation using Response Surface Methodology

Chlorpyrifos is a hazardous organophosphate pesticide used worldwide thus its biodegradation is need of the time. In the present study 13 bacterial strains were isolated from collected soil samples of different agro climatic regions and out of them one bacterial strain was screened out as potent degrader of Chlorpyrifos on the basis of percentage degradation using high pressure liquid chromatography (HPLC).
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Metabolic Effects of an Inositol-Resveratrol Nutraceutical Combination in Non-Diabetic Overweight/Obese Subjects with Altered Glucose Tolerance

Insulin resistance (IR) is almost constistently associated with overweight or obesity in both diabetic and non-diabetic subjects. Nutraceutical compounds improving insulin resistance (IR) may be useful in prevention and treatment of cardiovascular (CV) risk factors in metabolic diseases.
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Monotherapy versus Combination Therapy for the Treatment of Pseudomonas Aeruginosa in Cystic Fibrosis Patients

Infection with Pseudomonas aeruginosa in cystic fibrosis (CF) patients is a strong contributor to respiratory failure and associated mortality. Bacteria colonizing a cystic fibrosis lung commonly form biofilms that greatly contribute to increased antibiotic resistance and hypermutability. Antimicrobial treatment in these cases can be either through the use of a single agent (monotherapy) or through a combination of agents (combination therapy).
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Chronic Cough in Children with Rhinosinusitis Associated with Allergic Rhinitis and Rhinosinusitis Alone

Postnasal drip is one of the main causes of Upper Airway Cough Syndrome (UACS). Whether antibiotic targeted on rhinosinusitis accompanying UACS and chronic cough led to an improvement in a cough is controversy. Fifty-five schoolchildren, aged 4 to 14 years, were randomized into two groups: (1) Rhinosinusitis with allergic rhinitis, n = 20 (2) Rhinosinusitis alone, n = 35. The Spirometry, Forced Expiratory Volume in one second (FEV1), Forced Expiratory Flow (FEF) 25-75%, and Fractional Exhaled Nitric Oxide (FENO) were performed in all participants to rule out asthma or airway hypersensitivity. A pediatric allergist examined and recorded the clinical features, including stuffy nose, nasal discharge, postnasal drip, cough, facial, and halitosis. In addition, one senior radiologist examined and reported the results of water’s view and chest plain film for all schoolchildren. Both groups were given Amoxicillin/clavulanic acid twice a day for two weeks.
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Improvement of Bilateral Elevated Foveal Retinoschisis Following Sequential Vitrectomy with ILM Peel in a Patient with Enhanced S Cone Syndrome

To report outcomes after vitrectomy with ILM peel for bilateral elevated foveoschisis in a patient with Goldmann-Favre syndrome. Vitrectomy with ILM peel was done for one then the other eye of a 19 year-old patient with bilateral progressive enhanced s-cone syndrome associated elevated macular retinoschesis. Significant anatomical as well as visual improvements were noted in both eyes with regression of the macular edema, flattening of the retinoschesis, and a stable visual outcome thereafter. Despite the Inherent Risks of Surgery, Vitrectomy with ILM Peel may provide a possible surgical treatment option for patients with elevated retinal foveoschisis associated with enhanced S-cone syndrome.
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Selected Compounds Modulate Various Inflammatory Biomarkers in Lipopolysaccharide-Induced Macrophages of PPAR-α Knockout Mice

Inflammation has been implicated in cancer, diabetes and cardiovascular disease. We have recently screened several compounds that modulate inflammatory biomarkers (TNF-α, IL-1β, IL-6, and nitric oxide) in response to a variety of stimuli. Our hypothesis is that compounds with those anti-inflammatory properties will be useful for treatment of diabetes, cardiovascular disease, and other diseases based on inflammation.
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Efficacy of Vitamin C Vaginal Suppository in Treatment of Bacterial Vaginosis a Randomized Controlled Trial

The aim of the current study was to compare the efficacy and side effects of vaginal vitamin C suppository and vaginal metronidazole in treatment of bacterial vaginosis. Double-blind randomized controlled trial. The study included women who presented to the outpatient gynecological clinic with a diagnosis of bacterial vaginosis by amsels criteria. The included eligible women were randomly allocated in one of two groups: group I, including women who received vitamin C vaginal suppository once daily at bed time for 6 days; and group II, including women who received metronidazole 500 mg vaginal suppository once daily at bed time for 6 days. All included women were reviewed in 8-14 days after completion of treatment for reevaluation.
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Liquid Biopsy in Advanced Gastric Malignancy and Molecular Targeted Therapy; a Case Report and Update Pertaining Anti HER2-Neu Therapy

Human epidermal growth factor receptor 2 (HER2) is responsible for the pathogenesis and poor outcomes of several types of cancers, including advanced gastric and gastroesophageal junction cancer. Molecular-targeted drugs on the other hand, such as trastuzumab, prolong overall survival and progression-free survival in HER2-positive gastric cancer. The purpose of the case report is to evaluate the impact of delivering trastuzumab in advanced gastric cancer with concomitant HER2 mutation and amplification.
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An Early Description of Carcinosarcoma in 1883

By 1804, John Abernethy was aware of the existence of a tumor which he called carcinomatous sarcoma. In this context, this paper presentshow, in 1883, David Finlay fully documented a case whose data were indicative of the formation of carcinosarcoma in a woman sufferingfrom fibroids.
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Observations on Aeromonas Infection in 7 Patients with Acute Leukemia

Aeromonas infections in humans are becoming increasingly frequent. They have the potential to infect humans and are associated with a variety of illnesses, such as enterocolitis, septicemia, skin and soft tissue infectious and peritonitis.
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Adipogenesis in Obesity is Modulated by IP6 in Peanuts through Activation of the Nuclear Receptors (PPARs)

Increased life style changes have led to global epidemic of obesity. The global prevalence of obesity protracts to increase, with devastating consequences for overall health. Thus by exploring novel beneficial properties of natural products and their scientific indications are the need of the hour and can bring about a whole new revolution in nutraceutical industries and health care sectors.
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The Roles of Procalcitonin, C-Reactive Protein and Erythrocyte Sedimentation Rate in Predicting Bacteremia

The early differentiation between infectious and non-infectious sepsis remains a challenge due to the lack of a reliable, ready available and quick biomarker of bacterial sepsis. This study aims to determine the diagnostic accuracies of procalcitonin (PCT), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as individual and combined predictors of bacterial sepsis, when compared to the gold standard microbiological cultures
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Supernumerary Ectopic Tooth in Nasal Cavity - A Case Report

Supernumerary ectopic teeth are not uncommon; they present in abnormal location in oral cavity or may occupy a more unusual position, such as Maxillary Antrum. They are often diagnosed as incidental finding on routine Radiography; however, few may be symptomatic. Treatment options vary from endoscopic removal to conventional extraction by dental surgeon.
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Review on Pharmacological Activities of the Peptides from Scorpion Buthus Martensii Karsch

In China, the scorpion Buthus martensii Karsch is used as functional food and medicinal materials. The scorpion, scorpion venoms and their extracts are effective in treating a variety of nervous system diseases such as epilepsy, apoplexy pains and facial paralysis.
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Unusual Spontaneous Nasal Septal Abscess

A nasal septal abscess (NSA) is defined as a collection of pus between the cartilage or bony septum and the mucoperichondrium or mucoperiostium. It’s an uncommon disease that in the absence of early diagnosis and proper management may lead to lethal complications and cosmetic deformity.
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Editorial Board Members Related to iNOS

Ana Cristina Lindsay

Associate Professor
Department of Nutrition
University of Massachusetts Boston
United States

Songon An

Assistant Professor
Department of Chemistry and Biochemistry
University of Maryland Baltimore County
United States

Jayasimha Rao

Associate Professor
Jefferson College of Health Sciences
Department of Medicine
USA

SANTAMARIA RITA

Associate Professor
Department of Pharmacy
University of Naples Federico II
Italy

GEORGE DINOS

Associate Professor
Department of Biochemistry
University of Patras
Greece

KONSTANTINOS PAPAMICHAEL

Gastroenterologist
Medical School
University of Athens
Greece

Donald Cairns

Professor
School of Pharmacy and Life Sciences
Robert Gordon University
United Kingdom

GHASSAN M. MATAR

Professor
Department of Experimental Pathology, Immunology & Microbiology
Faculty of Medicine
American University of Beirut
Lebanon

KONSTANTINOS KANTARTZIS

Department of Internal Medicine
Division of Endocrinology, Diabetology
Nephrology, Vascular Disease and Clinical Chemistry
University of Tübingen
Germany

Nagendra K. Prasad

Assistant Professor
Division of Hematology and Oncology
Indiana University School of Medicine
United States
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