Articles Related to tumour

Background: Limited data on large cohort of patients with malignant tumors of the scalp are available in the literature. The aim of this study was to review a large cohort of patients with malignant scalp tumors to determine epidemilogy, tumor characteristics of this region and treatment. Materials and Method: A retrospective review of patients with malignant scalp tumors diagnosed histopathologically between 2005 and 2021 was performed. Demographic features and tumor characteristics were analyzed. Results: A total of 1080 patients (M: F 3,5:1) were treated and followed up for a mean period of 42 months (12-120 months). Age at diagnosis ranged from 12 to 98 years. Most malignant scalp tumors (95,1%) occurred in those 50 years or older and in bald patients (87%). Basal cell carcinomas (59,2%), squamous cell carcinomas (32,2%) and melanomas were the most common histologic types. Incidence was highest on the frontal of temporal region (66,1%). Recurrence was frequently in squamous and basal cell carcinomas but uncommon in melanoma. Conclusions: Tumors of the scalp accounted about 8,01 % of all skin cancers. Tend to be basal and squamous cell carcinomas, many of which occur in the temporal and frontal region of bald men. The outlook for patients with scalp tumor is positive, although we suggest excision margins of at least 3-4 mm and continued clinical vigilance is warranted given their higher recurrence rates.

View complete article: PDF  |  Full-text

Tumours of the parapharyngeal space are rare (less than 1% of head and neck tumours). They are of various etiologies, but pleomorphic adenomas from the parotid gland, nerve tumours and paragangliomas of the vagus nerve account for more than two thirds of cases.

View complete article: PDF  |  Full-text

Candida, a commensal of the oral and the vaginal cavity, sometimes turns invasive, in immunosuppressed individuals. The resultant lesion, known as invasive or aggressive candidiasis, can be extremely refractory to treatment. This is a case report of an ulcero proliferative lesion in the hard palate that mimicked an intra-oral neoplasm. The clinical picture was confused by the fact that the patient was a chain smoker, and also because the initial MRI images were strongly suggestive of an invasive malignancy. When clinical and radiological signs exactly mimic a malignancy, the picture is confusing.

View complete article: PDF  |  Full-text

Institutionalization and internationalization of modern interdisciplinary research belong to the essential components of scientific communications. Our purpose was to analyze scientometrically the dynamic science institutionalization on colorectal tumour markers as reflected in four information portals. In June 2017, a retrospective problem-oriented, title-word based search was performed in Web of Science Core Collection (WoS), MEDLINE and BIOSIS Citation Index (BIOSIS) of Web of Knowledge as well as in Scopus for 1987-2016.

View complete article: PDF  |  Full-text

In Morocco, through the finding of the Casablanca population-based registry, all cancers are estimated at 35000 new cases par year and 3.2% are aged less or equal 20 years.

View complete article: PDF  |  Full-text

A granular cell tumor of the breast parenchyma is a rare tumor accounting for 5-6% of all granular cell carcinoma and are mostly benign in nature.

View complete article: PDF  |  Full-text

Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves. They are usually asymptomatic, do not recur, and malignant transformation is rare.

View complete article: PDF  |  Full-text

Inflammatory Myofibroblastic tumour (IMT) is a rare spindle tumour that mimics malignant processes. It can affect any part of the body, but rarely occurs in the genitourinary tract. We report a case of urethral IMT in a 31-year-old pregnant female of 18 weeks gestational age.

View complete article: PDF  |  Full-text

A 13 year old, premenarchal, previously healthy girl presented to the emergency department of our hospital with complaints of vomiting, constipation and abdominal pain for past one day. The patient also complained of slowly increasing abdominal distension and mild abdominal discomfort since past four months.

View complete article: PDF  |  Full-text

Immunosenescence describes the decrease in immune function with advancing age, a phenomenon that is associated with changes in the B and T lymphocyte populations. CD8+ T cells display the most dramatic phenotypical and functional changes within the T cell compartment whereby the cohorts of effector and memory T cells expand while the total population and diversity of naive T cells both decline.

View complete article: PDF  |  Full-text

The aim of this review is to describe the role of nuclear imaging modalities using different radiotracers such as labeled nor-cholesterol, metaiodobenzylguanidine (MIBG) and deoxy-glucose (FDG) in the diagnostic evaluation of patients with adrenal tumours to perform lesion characterization in comparison with MR imaging.

View complete article: PDF  |  Full-text

A fifty three year old white female smoker with Lynch Syndrome was receiving adjuvant chemotherapy for node positive caecal adenocarcinoma. Interval investigations demonstrated a second primary gastric cancer with bilateral pulmonary nodules of indeterminate significance. Lung biopsy revealed Langerhans cell histiocytosis (LCH).

View complete article: PDF  |  Full-text

The recent resurgence of interest in m6A has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification. The m6A modification is a highly reactive and fluid modification which can respond rapidly to a broad variety of stimuli, and translate these signals into cellular activity. The little information that has been established on its functional capacity has opened up many new avenues of research and has tremendous implications for several fields of study.

View complete article: PDF  |  Full-text

A seventy five year male presented with acute onset right foot pain and swelling. Plain imaging revealed a lytic area in the medial and middle cuneiform bones of the right foot. Background history of resected pancreatic cancer and current presentation were consistent early diffuse disease recurrence of a pancreatic primary tumour. The presenting feature in this case was of symptomatic acrometastases, that is, metastases to the feet.

View complete article: PDF  |  Full-text

Adrenocortical carcinoma is a rare endocrine tumour with poor prognosis. Herein we report a case of adrenocortical carcinoma which was non-functioning, and non-metastasizing. A female patient presented with vague abdominal pain and palpable lump on examination. A large sized adrenal mass on Ultrasonography (USG) and computed tomography was revealed. USG guided fine needle aspiration cytology was performed, the smears were highly suspicious of malignancy.

View complete article: PDF  |  Full-text