Recent Articles

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease. Several indexes can measure SLE activity, and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) is one of them. The aim was to associate SLEDAI with inflammatory biomarkers present in serum (C3, C4, CH50, C-reactive protein, and creatinine), proteinuria (urine 24h) and urine NGAL in SLE patients. This study included 43 SLE patients who were arranged in two groups according to the value of SLEDAI. One group, SLEDAI 0-4 (n=25), included SLE patients with low activity, and the other group, SLEDAI >4 (n=18), included SLE patients form moderate to high activity. Level of urine NGAL (uNGAL) was determined by ELISA, and the data were analyzed using GraphPad Prism 5.

Aeric syndrome during a multiple trauma reflects the severity of this latter, which made mention to extra thoracic or intra thoracic lesion. This requires a good diagnostic and therapeutic strategy. We report the case of a young patient admitted to emergency in an array of closed multiple traumas where the etiological diagnosis was rare and unknown. This case highlights that a careful questioning and a good examination in admission can reveal earlier the diagnosis, the thing that was not well led in our case, because the patient was mute, anxious, and not cooperating making unnoticed rape history.

Obesity is a contemporary phenomenon that consumes an enormous and substantial public expense regarding health for needy countries. The amount spent only for the cost with the treatment of obesity for the SUS (The Unified Health System) was estimated around half a billion of reais in 2011 (Oliveira, 2013) [1]. In this scenery, the purpose towards prevention and control initiatives concerning these outlines must really become fundamental. This study has aimed to analyze the efficacy developed by a multidisciplinary team during a period of 12 months (from 2016 to 2017). The intervention has consisted in a number of periodic consultations supervised by this special team within food directions and physical training. All the data were synthesized and analyzed statistically through the Mcneunann Test, regarding the significance degree of p< 0.05. It has been observed in such results that most of the participants belong to feminine sex having from 45 to 81 years of age, a low schooling and a short monthly income. For the present, what must be said is that the intervention was wholly effective providing reduction of corporal measures, improvement in the quality of the diet consumed, besides a strengthening in the social network, empowering for the participants, further the expansion of knowledge about topics relative to food and nutrition. So, it can finally be suggested that initiatives towards obesity control are indeed effective and important and must be promoted everywhere.

Significant work has been attempted to better comprehend the attributes and mechanisms suggested in simulation and data mining in precedent research. More prominent understanding causes not only give progresses in numerous fields but also enable experts to better consider the last target.

The identification of altered splicing signatures in Myelodysplastic Syndromes (MDS) could likely provide key markers for diagnosis, prognostication and development of novel therapeutics. This review presents an insight into role of spliceosomal gene mutations in the pathogenesis of MDS, emphasizing on their clinical and prognostic significance. We also discuss emerging studies delineating the functional consequences of these mutations and pointing towards the emergence of a new leukemogenic pathway involving spliceosomal dysfunction.

To evaluate the quality of life and the impairment of the emotional function of women with breast cancer under chemotherapeutic treatment, in relation to sociodemographic and clinical characteristics. Observational, longitudinal, and analytical research; conducted between 2013 to 2015 with 67 women in three stages of chemotherapy treatment in a public referral teaching hospital in Paraná. Two questionnaires, one for socio-demographic and clinical data, and the Quality of Life Questionnaire-C30 were used for data collection.

The sedestation is defined as an act of sitting is a useful therapy for physiotherapy, have reported pulmonary effects ranging from increased lung compliance to improvement in oxygenation. There is lack of this study as a single therapy in critically ill patients, showing still not well defined.

This study was conducted to investigate the complete anatomy of the interforaminal area of the mandible. For the correct acknowledgement of the anatomical structures in this region is necessary, since it is especially important for planning implants. The CBCT and PAN images of 200 patients, taken for general dental diagnoses, were examined with regard to the mandibular incisive canal. The panoramic images were obtained using radiographic equipment Toshiba Corporation, J. Morita Mfg. Corp., Kyoto, Japan, while the cone-beam computed tomography dental imaging system GALILEOS, Sirona Dental Systems, Bensheim, Germany was operated.

Treatment of Hepatitis B infection is available with the help of existing drugs but the eradication of HBV infection is still under the pipeline. The application of novel drugs and gene-based therapies for HBV infection in need of the hour, however, the lack of efficient cell culture system, animal models for viral infection and replication acts as a major obstacle for novel therapies. This not only hampers the progress of HBV research but also stress the need for effective forthcoming therapeutics for Hepatitis B infection. Proteomic studies to understand the protein ubiquitination and to find molecular markers are the effective tools to study the HBV infection, pathogenesis and its control.

In the literature of fuzzy information measures, there exist many well-known parametric and non-parametric measures with their own merits and demerits. One important category of these measures is transcendental measures consisting of logarithmic, exponential and trigonometric fuzzy information and discrimination.

In the pre-anesthesia era, the anguish of planned surgical maneuver was dreadful and the experience of actual procedure “utterly speechless torture”. Although, the concept of pain relief and even total insensibility was not unfamiliar to medical profession, some of the “Big Giants in Medicine” believed “knife and pain as inseparable” and the efforts to relieve or prevent pain “in vain”. In such a situation the anesthesia,one of the greatest boons of science for mankind, “burst like a revolution on medical profession”. Despite hostility from religious sect, professional colleagues and civil societies the pioneers in discovery of anesthesia stood firm, unshaken by the negative criticism. Although the fate of the active contestant of “Ether Controversy” was mournful,their untiring and dedicated struggle to relieve the sufferings of mankind can never be underscored. Renowned Arab surgeon Ibn al Quff (1232-1286 AD) was the first to suggest anesthesia as independent speciality. However, it took almost 700 years for his dream to come true.

Neonatal hyperbilirubinemia is observed during the first week of life in approximately 60% of term infants and 80% of preterm infants. The aim of this study is to evaluate the predictive value of cord blood bilirubin and albumin in identifying neonates for subsequent hyperbilirubinemia. Cord blood samples (3ml) were collected from all newborns that complied with the protocol inclusion criteria. The samples were sent for the assaying of total, unconjugated, conjugated bilirubin, albumin levels and baby’s blood group and rhesus factor.

This study investigated price transmission and signals of the three major urban cowpea markets and their respective adjunct rural market across the zones and value chain in Niger state of Nigeria using monthly time series data spanning from January 2003 to December 2016. The selected urban markets were Bida, Minna and Kontagora, and their adjunct markets were Lafene, Zungeru and Manigi, respectively.

The records of 1198 crossbred cattle sired by 68 bulls were analyzed to estimate breeding values of sires using animal model Restricted Maximum Likelihood (REML), best linear unbiased prediction (BLUP), least squares methods (LSM) and simple daughter average ( D ) sire evaluation methods. The error variance of breeding values of sires were estimated and used in computing the relative efficiency of different sire evaluation methods. In the present study the least squares methods (LSM) have the lower error variance for Age at First Calving (AFC), First lactation milk yield (FLMY) and Lifetime lactation length (LTLL), while (BLUP) methods have the lower error variance for First lactation period (FLP), First dry period (FDP), First calving interval (FCI), First service period (FSP) and Lifetime milk yield (TLMY) as compared to other methods and accordingly, it was adjudged the most efficient sire evaluation method. In the present study, the higher value of coefficient of variation showing, there was very large variation in the herd for most of the traits under study. It indicated that the BLUP method is the best over the other three methods because estimated value of relative efficiency by BLUP method had smaller values than that of the other three methods. On the basis of the error variances of breeding values of sires the BLUP method was found most efficient sire evaluation method.

In this study, it was aimed to assess pomegranate (punica granatum L.) and grape (vitis vinifera L.) seed oil by comparing them physically and chemically. The fat output of the pomegranate (punica granatum L.) and grape (vitis vinifera L.) seeds was determined by the standard method of soxhlet extraction.

Attribution of etiology for disease syndromes is critical to guide appropriate public health interventions. Partial latent class analysis model (pLCM) methods have recently been developed to address this area of research; however, model parameters, assumptions, and performance are not well understood for the general etiology problem.

A 7 year old male child presented with recurrent forward falls, with a non-healing forehead wound. The falls were associated with brief period of unresponsiveness and eye blinking. Such episodes were 15-20 in number per day. Earlier treatment with carbamazepine only increased the number of falls. Imaging and electroencephalographic findings were suggestive of Doose Syndrome.

The selection of a surgical approach for the treatment of tibia plateau fractures is an important decision. Approximately 7% of all tibia plateau fractures affect the posterolateral corner. Displaced posterolateral tibia plateau fractures require anatomic articular reduction and buttress plate fixation on the posterior aspect. These aims are difficult to reach through a lateral or anterolateral approach. The standard posterolateral approach with fibula osteotomy and release of the posterolateral corner is a traumatic procedure, which includes the risk of fragment denudation. Isolated posterior approaches do not allow sufficient visual control of fracture reduction, especially if the fracture is complex. Therefore, the aim of this case report was to present a surgical approach for posterolateral tibial plateau fractures that both protects the soft tissue and allows for good visual control of fracture reduction. The approach involves a lateral arthrotomy for visualizing the joint surface and a posterolateral approach for the fracture reduction and plate fixation, which are both achieved through one posterolateral skin incision. Using this approach, we achieved reduction of the articular surface and stable fixation in patients at the final follow-up visit. No complications and no loss of reduction were observed. Additionally, the new posterolateral approach permits direct visual exposure and facilitates the application of a buttress plate. This approach does not require fibular osteotomy, and fragments of the posterolateral corner do not have to be detached from the soft tissue network.

Proximal humeral fractures account for approximately 5% of fractures seen in the emergency department. Despite this relatively high incidence only 15% of these fractures are displaced with an even smaller proportion being severely displaced enough to cause an axillary artery injury. We report a case of an elderly female patient who slipped and fell at home. She presented to our unit complaining of left shoulder pain and an inability to feel or move the involved limb. Imaging studies confirmed the presence of a severely displaced fracture of the proximal humerus and occlusion of the axillary artery. She was taken for open reduction and internal fixation of the proximal humerus followed by immediate axillary artery endovascular stenting.

The article provides some useful insights on bandage cloths as pointed out by some significant researches. Some work has been focused on medical bandages. In the construction of bandages, cotton, bamboo and cotton/bamboo have been selected. In order to enhance the functional properties finish has been given that include antimicrobial using triclosan, vitamin E and aloe vera. The woven bandages have been tested for antimicrobial activity, comfort and aesthetic property.