Recent Articles

Vascular variations of the head and neck are common, but oft en go unnoticed because they generally do not present clear clinical symptoms. Lack of awareness of the presence and location of such variations may result in iatrogenic complications or even fatalities. Physicians and surgeons should be cognizant of such variations given their potential clinical signifi cance.

Ovine footrot is the main cause of lameness in sheep around the world and is responsible for extensive economic and welfare impacts. It can be an extremely contagious disease, resulting from the invasion of the interdigital tissue by a complex mixture of bacteria, in which Dichelobacter nodosus is a required component. Strains of D. nodosus can be benign or virulent, but they are not always related with the clinical expression of footrot, complicating the diagnostic process. Several efforts have been made over recent decades to control the disease, but it remains endemic in the major sheep-raising countries of the world. The use of more efficient therapeutic procedures and better farm management practices or the development of new selective breeding tools and strategic vaccination protocols are some of the key measures that may improve footrot control in the future.

Planning for water resources development in a basin or over a region requires careful assessment of the available water resources and reasonable needs of the basin/region in foreseeable future for various purposes such as drinking water, irrigation, hydro-power, navigation, etc. There are several ongoing river water disputes between different states of India, especially in the peninsular region due to decrease in rainfall during the past 15 years or so. The sharing of water of the Mondovi River is a cause of dispute between the Governments of Maharashtra, Karnataka and Goa states. An attempt has therefore, been made to study the characteristics of rainfall distribution over the Goa state using daily and monthly rainfall data. The study mostly comprises of spatial distribution of rainfall, seasonal and annual rainfall trend, relationship between rainfall and rainy days, mean daily rainfall intensity (MDI) and yearly variation of rainfall as well. The results of this study would form basis for various studies in administrating fresh water sources, projecting the investments to prevent the urban areas from the flood and proper planning of the agricultural activities in the State.

Air pollution is a major and growing risk factor for ill health in India, contributing significantly to the country’s burden of disease. As per the Global Burden of Disease comparative risk assessment for 2015, air pollution exposure contributes to approximately 1.8 million premature deaths and 49 million disability adjusted life-years (DALYs) lost, ranking it among the top risk factors for ill health in India. Home to 10 of the top 20 cities with the highest annual average levels of PM2.5 as per the WHO Urban Ambient Air Quality Database (2016), and with several studies showing a worsening trend over the time, it is safe to say that rapid urbanization and industrial development have adversely affected urban air quality due to vehicular and industrial emissions. Simultaneously, over two-thirds of rural Indians caught in the ‘chulha trap’ use biomass fuels such as wood, dung or coal to satisfy their cooking and heating needs, resulting in smoke-filled homes and extremely high levels of exposure especially to women and children [1]. With respect to other cities of India, our smallest state Tripura (Agartala city) also have the high value of PM10 & PM2.5.The value of particulate matter is above the CPCB standards and also WHO standards. On the Basis of the study report we made some suggestion to overcome these conditions.

Although the use of physical restraint (PR) is accepted, it remains controversial as staff are required to balance professional, ethical and legal tensions between maintaining everyone’s safety, upholding human rights, and minimising harm. One such tension relates to the use of Wrist Flexion Techniques (WFT) used in some health, social care and custodial settings. WFT impose load onto the musculoskeletal structures of the wrist to gain control or compliance from a restrained person, and can result in discomfort, pain, injury, psychological trauma and be detrimental to therapeutic relationships. Current evidence and guidance on WFT are absent with debate existing as to whether WFT can be used without inducing pain. Twenty adults participated in the study. The mean discomfort angle was 90.1° (± 8.6) of flexion with 2.8 Kg (± 1.1) of force, and the mean pain angle was and 98.4° (± 7.9) of flexion with 4.4 Kg (± 1.8) of force, therefore only 8.3° of movement and 1.6 Kg of force separate pain free from pain inducing WFT. Genders did not differ in relation to angle of discomfort or pain. Females experienced discomfort with 1.1Kg less force (p = 0.021) and experienced pain with 1.7Kg less force (p = 0.023). This research challenges the assertion that WFT can exist as non-pain inducing and pain inducing PR techniques since the margin between them may be too small for practitioners to discriminate, particularly during the struggle of real world restraint. Further research may consider other potential pain inducing techniques, and the role and use of PIT during restraint.

Human female- derived osteoblast- like cells in culture (hObs) and the cell lines (SaOS2 and hFOB) express mRNAs involved in bone biology and physiology such as estrogen receptor α (ERα) and α (ERα), vitamin D receptor (VDR), 1α, 25 (OH) vitamin D3 hydroxylase (1OHase) and 12 and 15 lipoxygenases (12LO and 15LO). These mRNAs are modulated by estrogenic compounds. Since the skeletal protective effects of estrogens are not discernible in diabetic women, we tested the estrogenic modulations of these parameters in cells grown in growth medium containing high glucose (HG; 9.0g/L; 44mM) compared to normal glucose (NG; 4.5g/L; 22mM). HG significantly increased DNA synthesis (DNA) and creatine kinase specific activity (CK). Stimulations of DNA but not of CK by estradiol-17β (E2), by 4, 4’, 4’’-[4-propyl-(1H)-pyrazol-1, 3, 5- triyl] tris-phenol (PPT; ERa specific agonist), or by 2, 3-bis (4-hydroxyphenyl)-propionitrile (DPN; ER β specific agonist), were modulated by HG. HG Itself up regulated the expression of mRNA of 12LO and 15LO and to less extent ERβ and VDR, but had no effect on ERα and 1OHase mRNA expression. The different hormonal treatments modulated the expressions of VDR, 1OHase, 12LO and 15LO mRNAs which were reduced in HG, whereas the induction of their products 1α, 25 dihydroxy-vitamin D3 (1,25D) and 12- and 15- hydroxyeicosatetraenoic acid (12 and 15 HETE) were only slightly affected by HG. The exact mechanism of HG effects on bone cell responses and its relationship to human bone physiology is not yet clear.

The mental health as field of action for the physiotherapists is an important challenge that implies formation and investigation. The alterations of the mental health on a global scale are nowadays a problem of public health that it makes necessary that the professionals of the area of the health have a deeper knowledge on the topic to act of way adapted from the prevention and intervention.

Autism Spectrum Disorders (ASD) is regular heterogeneous neurodevelopmental disorder with symptoms like disability in social association, repetitive behavior interest and activities. Etiology of autism and different speculations of ASD were proposed keeping in mind the end goal to clarify the pathophysiology of ASD.

Late recourse to nephrology consultation remains a topical issue which concerns both developed and developing countries such that a majority of the patients are seen to be at an advanced stage of chronic kidney diseases. The aim of this study is to assess the clinical and paraclinical profile of patients referred for primary nephrological consultation.

In his Phenomenology of Spirit, Georg Hegel suggests that to be moral is to act in accordance with the moral tradition of one’s own country. 1 Hence, for Hegel, individuals act morally to the extent that they bear witness to the traditional moral climate in which they are situated. Thus understood, acting morally is a social phenomenon, comprised of attitudinal ebbs and flows that are nuanced by the changing moral traditions with which they inextricably interrelate. This much has proven particularly true with regard to the evolution of western attitudes toward death and [1,2] dying. 2 Indeed, significant traditional changes from the Middle Ages to the present day have transformed the hidden perceptions of death and dying (“thanatological apprehension”) of history into the increasingly rapid and perceptible expressions of [3] today.3

microRNAs play critical roles in cancer metabolisms. miRNA-181a-5p is significantly down-regulated in non-small lung cancer tissue and mesenchymal like lung cancer cells. Epithelial-mesenchymal transition mechanisms and cancer metabolism are controlled by the same signaling pathway.

Administration of exogenous progesterone or progestin can suppress estrous behavior in mares. Compounded long-acting formulations of progesterone are widely available. The objective of this study was to determine if a long-acting injectable progesterone formulation would suppress behavioral estrus in mares. Five mares were monitored daily by rectal palpation and transrectal ultrasonography to insure that all mares were cycling normally. Endogenous progesterone was removed through lysis of the corpus luteum seven days post-ovulation with prostaglandin F2 alpha (PGF2α). Two days following PGF2α administration, mares received 2 g of long-acting progesterone intramuscularly. Estrous behavior was determined daily by individually exposing mares to a stallion beginning two days before injection of long-acting progesterone until ovulation occurred. Serum progesterone concentrations were significantly elevated (>2 ng/mL) for 10 days following treatment with a long-acting injectable progesterone. Behavioral estrus suppression during this period was minimal and not significant. All mares developed local injection site reactions and half the mares developed febrile responses following treatment. In conclusion, the long-acting compounded formulation of progesterone elevates progesterone concentrations for 10 days but does not suppress estrous behavior to a stallion. Due to the side effects associated with this treatment, long-acting formulations of injectable progesterone are not appropriate for use in performance horses.

Phenylbutazone (PBZ) is commonly used in equine patients for treatment of orthopedic injuries. Phenylbutazone may adversely affect bone healing because of suppression of prostaglandin production. We hypothesized that administration of the prostaglandin analog misoprostol would enhance bone healing and mitigate the untoward effects of PBZ on bone response to injury in horses. The objectives of this study were to determine whether the administration of misoprostol would enhance bone healing and whether concurrent administration of PBZ and misoprostol would mitigate the untoward effects of phenylbutazone. Twenty horses were randomly assigned to one of four groups (n=5 per group): Group 1 (untreated control), Group 2 (phenylbutazone alone), Group 3 (misoprostol, alone), or Group 4 (concurrent treatment with phenylbutazone and misoprostol). A 4.5-mm diameter uni-cortical bone defect was created in one metacarpal III bone of all horses. Fluorochromic bone labels were administered intravenously on Days 0, 7, and 14. Computed tomographic osteoabsorptiometry and histomorphometric analyses were performed on the harvested metacarpal bones. Phenylbutazone treatment caused a decrease in endosteal new bone formation. Administration of misoprostol appeared to mitigate the magnitude of the PBZ effect on new bone formation (endosteal in-growth, p

One of the tropical fruits with high economic value is pineapple. Smooth cayenne (smooth leaf) and Red Spanish (Rough leaf) are the two cultivars of pineapple grown in the world. They grow in the soil and resemble epiphytes in that their roots are intolerant of poor soil aeration.

Bats (order Chiroptera) are one of the diverse mammal groups and distinguishing from other mammals by their real flight. Bats have long been postulated to play essential roles in agriculture including arthropod suppression, seed dispersal, pollination, biological indicator, organic fertilizer provider (guano) and improving soil structure, etc.

Ticodendron incognitum the only species of the Ticodendraceae family was discovered in Costa Rica in 1989 and currently there are no reports on its chemical composition or biological activity.

The use of organic fertilizer as an alternative to inorganic fertilizer increased among subsistence farmers in rural areas in meremieti. Despite the fact that, no clear recommendation exist for the application of rate of organic fertilizer on vegetable. Field experiment was conducted to evaluate the different combination of organic and inorganic fertilizer on yield and yield component of cabbage.

Part of the study was to assess the concentration of secondary metabolic (total: phenolic, flavonoid, and proanthocyanidin, tannin) and the antioxidant activities in methanol (MeOH) and methanol-water (MeOH-H2O) extract of GnA.