Top Links

Articles Related to inflammatory

Standardization of Pro-Inflammatory Cytokines (IL-1 & TNF-α) and Haematological Biomarker as an Early Assessment of Health Status in Adult Healthy Pigs

The study was aimed to standardize pro-inflammatory cytokines and haematological biomarker level in visually adult healthy swine as an early health check-up scanner. In the present study, total six (6) crossbreed pigs (Yorkshire × Swedish Landrace) with similar age group (3 years) and unisex (male) with average body wt (140 kg) were selected for sampling.
View complete article: PDF  |  Full-text

An Adjuvant Approach to Alleviate Reoccurring or Treatment Resistant Symptoms of IBD in Companion Animals

Inflammatory bowel disease (IBD) is a common yet distressing condition afflicting tissues of the gastrointestinal (GI) tract in companion animals; symptoms include vomiting, diarrhoea, loss of appetite and weight loss. Pathogenesis of IBD may link to both diet and parasitic or bacterial infections of the gut. Although current treatments may provide some relief to the animal, unfortunately recurrent flaring of symptoms is not uncommon. Therapeutic interventions available to the veterinarian include those that focus on treating any underlying infection and or a change in diet, both employed with the aim of reducing inflammation.
View complete article: PDF  |  Full-text

Inflammatory “Endotheliopathy’’ with COVID 19 Infections in Children, Unanswered Questions for Management Post Recovery

Recent studies from U.K, US and Canada have reported a unique presentation of the novel corona virus (SARS-CoV-2) in the pediatric age group. High fevers, rash, multiorgan involvement was a recurrent mode of presentation; with an overall case fatality rate in the US-Canadian PICU consortium group was reported to be approximately 4.2% [1-7]
View complete article: PDF  |  Full-text

Intracranial Inflammatory Pseudotumor: A Case Report and Review of the Literature

Inflammatory pseudotumors are lesions characterized by inflammatory cell infiltration and fibrosis. Central nervous system (CNS) inflammatory pseudotumors are much rarer, and generally manifest in the sellar and parasellar regions. We report a patient with an inflammatory pseudotumor in the temporal and occipital lobes treated in our department in 2017, and present a literature review. We discuss the etiology, imaging, pathology, and treatment of intracranial inflammatory pseudotumors.
View complete article: PDF  |  Full-text

Early Spondyloarthritis Presenting as Premenopausal Osteoporosis and Multiple Vertebral Fractures: A Case Report

We report a 30-year-old woman who presented during pregnancy with mechanical type backache due to non-traumatic multiple vertebral fractures. In-depth the assessment revealed multiple risk factors for osteoporosis, including adolescent steroid use for asthma, prolonged breastfeeding, and vitamin D deficiency. She also had persistently elevated inflammatory markers with radiological evidence of early inflammatory Sacro-ileitis. The rheumatoid factor and HLA B27 were negative. She was successfully managed with NSAIDS, zoledronic acid, and calcium supplementation. This is an example of early inflammatory arthritis in the background of multiple risk factors causing osteoporosis severe enough to cause fragility fractures. This signifies the importance of screening for multiple risk factors in pre-menopausal osteoporosis even in the presence of one or two identified risk factors.
View complete article: PDF  |  Full-text

The ACAI (Euterpe oleracea Mart.) Pulp Consumption Improves Blood Pressure Levels in Women with Higher Concentrations of Interferon-Gamma

Interferon-gamma (IFN-γ) is associated with the inflammatory responses modulation, which could culminate in chronic metabolic diseases. In this context, the aim of the present study was to evaluate the effect of the acai (Euterpe oleracea Mart. mart.) pulp consumption on the anthropometric, clinical and biochemical parameters in women clinically healthy, with IFN-γ, respectively, smaller and higher than 5 pg/mL. Twenty four women in G1 (with IFN-γ concentrations smaller than 5 pg/mL) and sixteen in G2 (with IFN-γ concentrations greater than 5 pg / mL), consumed 200g per day of acai pulp during four weeks. Anthropometric and body composition measurements, biochemical and clinical data were evaluated before and after the intervention
View complete article: PDF  |  Full-text

Is there Correlations among SLEDAI, Pro-Inflammatory Biomarkers and Urine NGAL in SLE?

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease. Several indexes can measure SLE activity, and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) is one of them. The aim was to associate SLEDAI with inflammatory biomarkers present in serum (C3, C4, CH50, C-reactive protein, and creatinine), proteinuria (urine 24h) and urine NGAL in SLE patients. This study included 43 SLE patients who were arranged in two groups according to the value of SLEDAI. One group, SLEDAI 0-4 (n=25), included SLE patients with low activity, and the other group, SLEDAI >4 (n=18), included SLE patients form moderate to high activity. Level of urine NGAL (uNGAL) was determined by ELISA, and the data were analyzed using GraphPad Prism 5.
View complete article: PDF  |  Full-text

Invitro and Invivo Anti-Inflammatory Activity of Bauhinia X Blackeana Linn Leaves

The present study is to investigate the anti-inflammatory activity of Bauhinia X blackeana leaves by in vivo on rats and in vitro using HRBC membrane stabilizing method. Diclofenac sodium was used as reference drug for comparison. The methanolic extract showed significant activity when compared to the standard drug.
View complete article: PDF  |  Full-text

A Review on Antioxidant, Anti-Inflammatory and Gastroprotective Abilities of Mango (Magnifera indica) Leaf Extract and Mangiferin

Mango (Mangifera indica Linn.) trees have been cultivated and grown in Southern and Eastern India for thousands of years and have slowly spread all over the world. For over 4,000 years various parts of mango trees including leaf and fruit pulp have been extensively used in Ayurvedic and Unani medicines.
View complete article: PDF  |  Full-text

Internal Inflammatory Root Resorption. Management with Mineral Trioxide Aggregate and Gutta-Percha

Early diagnosis and accurate treatment are essential for Internal Inflammatory Root Resorption (IIRR) control. The aim is to present the sequence of diagnosis, treatment and follow-up of an IIRR using gutta-percha (GP) and Mineral Trioxide Aggregate (MTA) as obturation materials. This study exhibits an IIRR case in the #9 tooth of a 64-year old patient. History refers to a horse’s kick suffered ten years earlier. The tooth was asymptomatic during the interim time period but eventually the patient experienced symptomology. Following a detailed exam, a treatment plan was reached to save the tooth and maintain its functionality.
View complete article: PDF  |  Full-text

Compartmentalization Modules of Inflammatory Response are Centered on the Epithelial-Mesenchymal Transition of Transforming Cells in Carcinogenesis

The epithelial-mesenchymal transition (EMT) event in carcinogenesis is dependent on multiple operant pathways of master transcription as proposed for NF-kappaB and in terms of the initiated progression of malignant transformation. Inflammation is a primarily compartmentalized series of distinct and overlapping systems that induce and enhance multifocal operabilities within both the nucleus and cytoplasm by systems of enhancer/inhibitory modes of modulation of multi-gene transcription.
View complete article: PDF  |  Full-text

A Randomized Double-Blind Placebo Controlled Clinical Trial Evaluating the Effects of an Investigational Study Product on Exercise Induced Muscle Soreness, Markers of Inflammation, Muscle Damage and Exercise Performance in Healthy Males

Gherkin, a pure botanical extract from cucumber is a phytonutrient rich vegetable which may have been shown to have anti-inflammatory and pain relieving properties. The purpose of this randomized double-blind placebo study was to determine the effects of Gherkin (Cuvitus™, Actido®)on exercise performance, markers of inflammation and acute muscle soreness in healthy males.
View complete article: PDF  |  Full-text

Long Exposure to CdS-Dextrin Nanoparticles Induces an Immunomodulatory and Anti-Inflammatory Effect in Rats

Male Wistar rats were treated daily and intraperitoneally with CdS-Dextrin nanoparticles (100 μg/kg) during 30, 60, and 90 days. The effect of subacute and chronic administration of CdS-Dextrin nanoparticles on CD4/CD8 subpopulations of thymocytes, spleen-derived T cells, and peripheral blood CD4/CD8/CD3 T cells were analyzed by flow cytometer using a Rat T Lymphocyte Cocktail. An indirect ELISA kit analyzed cytokine Th1/Th2 levels. A DNA content and cell cycle analysis was carried out in bone marrow cells by flow cytometry. We also analyzed the presence of CdS-Dextrin nanoparticles in the thymus and spleen.
View complete article: PDF  |  Full-text

Selected Compounds Modulate Various Inflammatory Biomarkers in Lipopolysaccharide-Induced Macrophages of PPAR-α Knockout Mice

Inflammation has been implicated in cancer, diabetes and cardiovascular disease. We have recently screened several compounds that modulate inflammatory biomarkers (TNF-α, IL-1β, IL-6, and nitric oxide) in response to a variety of stimuli. Our hypothesis is that compounds with those anti-inflammatory properties will be useful for treatment of diabetes, cardiovascular disease, and other diseases based on inflammation.
View complete article: PDF  |  Full-text

MRI of the Psoas Major Muscle: Origin, Attachment, Anatomical Variants and Correlation with the Lumbar Disc Extrusion

To verify the psoas major muscle (PMM) anatomical origin and variants, to evaluate the PMM attachment to the lumbar disc and variants, and to search for correlation between the anatomic variants of PMM attachment to the disc and disc extrusion.
View complete article: PDF  |  Full-text


Editorial Board Members Related to inflammatory

Michael P. Namaka

Associate Professor
Faculty of Pharmacy and Medicine
University of Manitoba
Canada

Joseph Prandota

Emeritus Full Professor
Department of Pediatrics & Clinical Pharmacology
Faculty of Health Sciences
Wroclaw Medical University
Wroclaw
Poland

MICHAEL VAN DOREN JOHNSTON

Professor
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States

YUNBO LI

Professor
Department of Pharmacology
Campbell University School of Osteopathic Medicine
United States

Chunying Li

Assistant Professor
Department of Biochemistry and Molecular Biology
Wayne State University School of Medicine
United States

SCOT MICHAEL LEWEY

Medical Director
Adult Gastroenterology Program
Castle Rock Adventist Hospital
United States

Parameswaran Ramakrishnan

Assistant Professor
Experimental Pathology
Case Western Reserve University
United States

MICHAEL P. SHERMAN

Professor Emeritus
Department of Child Health
Division of Neonatology
University of California-Davis School of Medicine
United States

Walter Royal

Professor
Department of Neurology
University of Maryland
United States

Tao Liu

Children's Cancer Institute
University of New South Wales
Australia
Submit Manuscript


Open Access Journals

View All Journals