Articles Related to CAPS
Supercapsular Percutaneously-Assisted Approach Versus Conventional Posterolateral Approach for Primary Total Hip Arthroplasty: A Prospective Randomized Controlled Study
Background: Super capsular percutaneously-assisted total hip (Super PATH) approach has been regarded as one of minimally invasive and muscle sparing technique, which accesses the hip maintaining integrity of the external rotators and capsule. The purpose of this study was to compare the Super PATH approach with the conventional posterolateral approach in terms of early clinical outcomes and radiological results.
Capsaicinoids Increase Resting Metabolic Rate in Healthy Individuals under Fasting Condition
Obesity is a chronic metabolic condition of energy imbalance where energy intake exceeds energy expenditure. Resting energy expenditure (REE) represents calories burned at rest and accounts for >60% of total energy expenditure and is an important target for management of obesity. Capsaicinoids, extracted from Capsicum annuum have previously been shown to increase metabolism, lipolysis & induce satiety.
Encapsulation Applications and Production Techniques in the Food Industry
The encapsulation method is a process applied to increase the shelf life of the active food components, ensure their stability, perform
their controlled release and improve their functional properties. Active particles such as fatty acids, peptides, vitamins and probiotics
are coated with coating materials such as starch derivatives, gelatin, gum arabic to eliminate external effects.
Bioequivalence between Two Capsules of Pirfenidonein Healthy Subjects under Fed Condition
Pirfenidone capsules are indicated for the treatment of patients with Idiopathic pulmonary fibrosis. The Bioavailability of two
formulations containing pirfenidone 267 mg hard gelatin capsules was compared in a bioequivalence study under fed conditions. The
study was single dose, randomized, open label, two-period crossover, with Brazilian healthy subjects, males and nonpregnant females.
Can Myofascial Treatment with Pulsating Vibrations Improve Mobility for Patients with Frozen Shoulder? A Case Study
Thousands of patients are annually diagnosed with Frozen Shoulder (FS) or adhesive capsulitis, where the joint capsule contracts and becomes less flexible. The condition is painful, with reduced range of motion (ROM) in the shoulder and arm and causes great suffering, often with difficulty sleeping and greatly reduced work ability. The treatment given today is partly conventional treatment with cortisone or NSAID preparations as well as physiotherapy and other therapeutic treatment which usually have limited effect. The study investigates whether myofascial treatment, using a device generating deep pulsating vibrations, can provide increased ROM and facilitate for these patients. 23 patients diagnosed with FS were included in the study. Three treatments were performed, within set time intervals. The ROM was measured before and after each treatment, pictures were taken with a thermography camera and angles were measured. The result showed that 87 percent got an increased ROM by 30 degrees or more, that 52 percent of the patients improved
ROM by 60 degrees or more, and that 30 percent regained full ROM. 61 percent of the patients also reported improved quality of sleep. The study indicates that this treatment could possibly improve ROM and well-being for patients with FS. Further studies are recommended to evaluate and validate these findings. A validated treatment of FS could mean great socioeconomic benefits and an increased quality of life for patients diagnosed with FS.
An Observational Chart Review of a Comparison of Generic to Reference Liposome-Encapsulated Doxorubicin Hydrochloride in Subjects with Epithelial Ovarian Carcinoma Who Have Failed Platinum-Based Chemotherapy
This study tested for the effects of generic liposome-encapsulated doxorubicin hydrochloride (generic doxorubicin) compared to reference-pegylated liposomal doxorubicin hydrochloride (reference doxorubicin) as a treatment for patients afflicted with epithelial ovarian carcinoma whose disease has progressed after platinum-based chemotherapy. Chart-reviews of actual patients enrolled in a community-based NIH trial suggest that both generic and reference liposomal doxorubicin hydrochloride (HCl) are equally effective
as treatment for ovarian cancer carcinoma.
Bioequivalence Study of Two Oral-Capsule Formulations of Omeprazole 20 mg in Combination with Sodium Bicarbonate in Healthy Mexican Adult Volunteers
In Mexico, the immediate-release formulation of omeprazole 20 mg in combination with 1100 mg of sodium bicarbonate (oral capsules) is indicated for patients over 18 years for the treatment of gastritis, reflux, heartburn and the sensation of emptiness caused by the excessive acid production.
Bioequivalence Study of Two Oral-Capsule Formulations of Pregabalin 300 mg in Healthy Mexican Adult Volunteers
Pregabalin is a ligand for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. It has anticonvulsant, analgesic, and anxiolytic activity. The bioequivalence of a test formulation was evaluated with respect to its corresponding reference drug formulation of oral pregabalin 300 mg, administered as a capsule. This randomized-sequence, single-dose, single-blind, two-period crossover design under fasting conditions was done on 25 healthy Mexican adult subjects including both genders. There was a seven-day washout period.
Mesenchymal Stem Cells from Different Tissues: Immune Status and Activity
Mesenchymal stem cells (MSCs) have been found in almost all tissues and due to their regenerative properties represent promising tools in cell-based therapy. Role of MSCs in tissue repair is strongly governed by their interplay with immune cells and regulating factors.
Schwannoma Palate in Children: Rare Case
Schwannoma is a benign tumor that originates from the presence of Schwann cells of the peripheral nerves. They are usually asymptomatic, do not recur, and malignant transformation is rare.
Canakinumab in the Treatment of Erosive Hand Osteoarthritis: A Case Series
Erosive hand Osteoarthritis (EOA) is a common and debilitating form of hand OA for which there are no proven or efficacious therapies. Interleukin-1 beta (IL-1β) plays a prominent role in OA joint inflammation. Canakinumab is a selective IL-1β inhibitor.
Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets
The purpose of this study is to synthesize and characterize nanodroplets, loaded with docetaxel for treatment of prostate cancer under MR-guided focused ultrasound. Water insoluble docetaxel encapsulated in nanodroplets is expected to be delivered into tumors with greater efficiency while minimizing drug related systemic toxicities when used in combination with focused ultrasound. The sequence of our studies toward development and characterization of docetaxel-loaded nanodroplets is as follows. First, we developed methods for synthesis of ultrasound-responsive, docetaxel-loaded nanodroplets (Doc-nd) by a solid dispersion technique. Secondly, we characterized Doc-nd by its morphology and size distributions using a dynamic light scattering (DLS) method.
Croscarmellose Sodium Efficiency in the Development of a Generic Capsule Formulation of Piroxicam, Comparable Dissolution Profile to the Innovator Product, Feldene
The objective of this study was to evaluate the encapsulation performance of Croscarmellose sodium, a superdisintegrant in a low-dose, poor-solubility drug formulation and the in-vitro dissolution performance of the Piroxicam capsules. Preparation, characterization and evaluation of the effects of the different concentrations of carmellose sodium and the amount of dried starch on in-vitro dissolution of Piroxicam capsules. Piroxicam was chosen for its very low solubility in biological fluids, which result in poor systemic bioavailability after oral administration. Piroxicam can be categorized as Class II drugs according to the Biopharmaceutics Classification System.
Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs
The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion).
Perspectives and Potential Applications of Ruthenium-Based Nanocarriers for Cancer Therapy
Cancer is a highly heterogeneous disease characterised by continuous uncontrolled growth and expansion of abnormal cells. In general, in tumor cells the signalling pathways regulating cellular processes, as cell growth and division and cell to cellcommunication result strongly altered.
Editorial Board Members Related to CAPS
NORMA RANGEL
Professor Research
Division of Graduate Studies and Research
Institute of Technology Aguascalientes (ITA)
Technological Institute of Aguascalientes (ITA)
Mexico
Division of Graduate Studies and Research
Institute of Technology Aguascalientes (ITA)
Technological Institute of Aguascalientes (ITA)
Mexico
QINGRONG HUANG
Professor
Department of Food Science
Rutgers University
United States
Department of Food Science
Rutgers University
United States
V. Sankar
Professor & Head
Department of Pharmacy Practice
PSG College of Pharmacy
India
Department of Pharmacy Practice
PSG College of Pharmacy
India
Ahmed S. Zidan
Associate Professor
Department of Pharmaceutics and industrial pharmacy
Zagazig University
Egypt
Department of Pharmaceutics and industrial pharmacy
Zagazig University
Egypt
ALAA EL-DEEN BAKRY YASSIN
Associate Professor
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
Department of Pharmaceutical Sciences
King Saud bin Abdulaziz University for Health Sciences
Saudi Arabia
JACQUES MARESCAUX
Professor
Department of Surgery
Research Institute Against Digestive Cancer
France
Department of Surgery
Research Institute Against Digestive Cancer
France
Shaddel Rezvan
Visting Scholar
Food Science and Technology Department
Rutgers University
USA
Food Science and Technology Department
Rutgers University
USA
Khalid M. El-Say
Associate professor
Department of Pharmaceutics and Industrial pharmacy
King Abdulaziz University
Saudi Arabia
Department of Pharmaceutics and Industrial pharmacy
King Abdulaziz University
Saudi Arabia
Yao Olive Li
Assistant Professor
Department of Human Nutrition & Food Science
California State Polytechnic University
United States
Department of Human Nutrition & Food Science
California State Polytechnic University
United States
ANASTASIOS KOULAOUZIDIS
Associate Specialist Gastroenterologist
The Royal Infirmary of Edinburgh
United Kingdom
The Royal Infirmary of Edinburgh
United Kingdom