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Articles Related to apoptosis

Predicting Multi-Drug Inhibition Interactions based on Signaling Networks and Single Drug Dose-Response Information

Inhibiting multiple pathways/targets with combination drug therapies is widely used to maximize therapeutic benefit in many diseases. Therapeutic success can often be improved by concurrently and/or sequentially inhibiting multiple pathways/targets by combining drugs with different mechanisms of action.
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Human Neutrophils in Patients with Positive Serology for Chagas Disease

Polymorphonuclear (PMN) neutrophil leukocytes are cells of innate immunity recognized in a peripheral blood smear because of their particular multilobed nucleus. Ring shaped nucleous are typical in rats and mice, being described in some pathologies in humans as well as in healthy subjects.
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Requirements for Cryopreservation of In Vitro-Produced Bovine Embryos by a Standard Method of Vitrification

In relation to assisted mammalian reproduction, the goal of cryopreservation is to preserve without significant loss of viability a stock of gametes and/or embryos with a view to thawing those cells for use in in vitro reproduction treatments. There are numerous cryopreservation protocols, which vary in terms of cryoprotectant used, storage temperature, freezing and thawing rates, and the particular cells that they are suitable for preserving.
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Fangchinoline Inhibits Breast Tumor Proliferation and Induces Apoptosis in MDA-MB-231 Cell Line in Vivo

Immunohistochemistry (IHC) was used to determine the protein levels of p27, CD117 and ki67 in tumor tissue of xenograft. After treatment of Fan, the morphologic changes were observed by DAPI staining, Hoechst staining and TUNEL detection under fluorescent microscopy.
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Anti-GnRH Receptor Monoclonal Antibodies, First-In-Class GnRH Analog

A monoclonal antibody (Mab) designated as GHR106 was generated against the extracellular domain (N1-29 synthetic peptide) of human gonadotropin releasing hormone (GnRH) receptor. It is a first-in-class GnRH analog and can serve as a drug candidate for potential applications in the treatment of human cancers and/or fertility regulations.
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Pharmacy Compounding Quality Control and Pharmaceutical Development Strategies for Seventeen alpha Hydroxyprogesterone Caproate in Prevention of Preterm Delivery

Seventeen alpha hydroxyprogesterone caproate (17-OHPC) is the only FDA-approved drug labeled for prevention of preterm delivery. This drug is also available as a compounded product from licensed compounding pharmacies. This article reviews the FDA approval history and pharmacy compounding quality control data of 17-OHPC, as well as briefly discusses possible future pharmaceutical development strategies for 17-OHPC.
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Salmonella Serovars and Their Host Specificity

Salmonella is a causative agent for a wide variety of pathological diseases in humans, cattle, poultry and other farm animals and hence Salmonella infections are a major cause of concern to humans, veterinary animals and to food industry.
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New Adipocytokines

They are cytokines secreted by adipose tissue considered to be immunomodulating agents, however they can be more accurately put into the larger, growing list of adipose-derived hormones.
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MAPK Pathway in Skeletal Muscle Diseases

Mitogen-Activated Protein Kinase (MAPK) pathway is a signal transduction pathway that functions in a wide range of physiological and pathophysiological cellular events including cell proliferation, differentiation, apoptosis, migration, inflammation, metabolic disorders and diseases.
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Editorial Board Members Related to apoptosis

Jinlian Hua

Professor
Shaanxi Centre of Stem Cells Engineering & Technology
Key Lab for Animal Biotechnology of Agriculture Ministry
Northwest A&F University
China

Shigemi Matsuyama

Associate Professor
Division of Hematology/Oncology
School of Medicine
Case Western Reserve University‚Ä®
United States

Yuchuan Ding

Professor
Department of Neurosurgery
Wayne State University School of Medicine
United States

Grant Dewson

Laboratory Head
Cell Signalling and Cell Death Division
Walter & Eliza Hall Institute of Medical Research
Australia

Tao Liu

Children's Cancer Institute
University of New South Wales
Australia

HONGYU LI

Associate Professor
Department of Gastroenterology
Shenyang Northern Hospital
China

Charles J. Malemud

Professor
Department of Medicine and Anatomy
Case Western Reserve University
United States

Zodwa Dlamini

Professor
Translational Oncogenomics & Molecular Pathology
College of Agriculture & Environmental Sciences
United Kingdom

MING-JEN CHEN

Assistant Professor
Division of Gastroenterology
Department of Internal Medicine
Mackay Medical College
Taiwan

Chiang-Ting Chien

Professor
Department of Biology
National Taiwan Normal University
Taiwan
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