Recent Articles

Brain water metabolism ensures the processes of cellular communication, the transit of the signaling molecules, neurotransmitters, cytokines, and substrates, participates in the clearance of pathogenic metabolites. Many neurological conditions that present serious clinical problems arise from the altered fluid flow (e.g. Alzheimer’s disease, idiopathic normal pressure hydrocephalus, migraine, traumatic brain injury and stroke).

The surgical procedure for myocardial revascularization (MRI) may compromise chest stability, compliance and range of motion (ROM) of the shoulder joint due to sternotomy and knee joint due to saphenectomy.To evaluate the impact of myocardial revascularization surgery on upper and lower limb ROM

MicroRNAs (miRNA) are potent regulators, controlling multiple biological processes, including cell growth, differentiation, cell death, development and immune responses. With emerging data supporting that miRNAs play a central role in gene dysregulation in human malignancies, unraveling the miRNA genetic variations in cancer is essential and critical if we want to develop better diagnostic and prognostic system for our patients.

Mean platelet volume MPV that is included in CBC, will be larger with platelet destruction problems as in Neonatal sepsis NS or when the body is producing increased numbers of platelets. Also, NS is associated with increased production of reactive oxygen species that will lead to consumption of specific antioxidant molecules like uric acid. The aim of the work: to determine the role of MPV and uric acid levels in the early diagnosis of NS.

The examination of saliva traces left on cigarette butts as evidences are complicated due to the availability of biological material in trace amounts and its rapid degradation due to extreme effects of environmental factors. This study is aimed to assess the DNA purity and quantify the amount of DNA preserved in saliva found on cigarette butts subjected to various temperatures and humidity. Isolation of cell material from biological traces on forensic evidence is often a serious challenge to solving forensic cases.

Deep endometriosis is a disease with a great negative impact on patient quality of life, requiring surgical treatment in tertiary centers and surgeons highly skilled in performing complex surgeries, and is associated with high rates of morbidity and related complications. We evaluated all cases of deep endometriosis operated by the same surgeon since 2011 to evaluate the profiles of patients, sites and organs affected, surgical indications and complications and to propose a standardization of the surgical technique used in our service.

Gastroschisis (GQS) and omphalocele are congenital defects of the abdominal wall; The GQS is a defect usually on the right side of the umbilical cord, where there is exposure of the intestinal loops and there is no membrane that covers them; The omphalocele is a defect through the umbilical cord, in which there is a herniation of the intra-abdominal organs, which are covered by a membrane. GQS is generally associated with minor abnormalities of the digestive tract and generally does not have an association with severe congenital abnormalities. The diagnosis can be made prenatally by Ultrasound (USG). The objective is to present a clinical case of gastroschisis associated with severe midline congenital anomalies, such as ectopia cordis, which is not frequent in these patients [1-4].

Here, we present a 43-year-old male with osteogenesis imperfecta (OI) with previously placed intramedullary growing rods that sustained an atypical femur fracture (AFF) following long-term bisphosphonate use. He additionally experienced a non-traumatic ipsilateral femoral neck fracture that was successfully managed with operative stabilization. Despite previous reports following successful conservative management for AFF in patients with OI, nonunion developed requiring osteotomy and surgical stabilization.

We present a case report of a patient with Mounier-Kuhn syndrome. The clinical, radiological and endoscopic illustrations contribute to the awareness and recognizability of this rare and under-diagnosed pulmonary syndrome. It is characterized by tracheobronchomegaly and tracheomalacia, leading to ineffective mucociliary clearance, recurrent respiratory infections and bronchiectasis. Computed tomography is the golden standard for diagnosis. Etiology remains unknown. Prognosis depends on adequate treatment and prevention of respiratory infections.

1-D, 2-D gel electrophoresis, mass spectrometry and bioinformatics analysis were established and utilized to examine the changes in protein expressions associated with germination of Ceiba pentandra seeds.The change in protein pattern was analysed by 1-D and 2-D gel electrophoresis for better separation and to ascertain the pattern of protein mobilization during germination.

In 1987, the World Health Organization Global Programme on AIDS identified three phases of the HIV/AIDS epidemic: the epidemic of HIV, the epidemic of AIDS, and the epidemic of stigma and discrimination. The report also notified that the third phase is a central issue to the global AIDS challenge and the disease itself. Despite continued multilateral efforts to tackle HIV/AIDS, stigma and discrimination remain among the most poorly understood aspects of the epidemic. In this paper, stigma and discriminatory attitude among high school students was assessed.

Joint endoprosthesis are standard treatment in orthopedic surgery, but the risk of infection represents a major drawback for elderly patients with comorbidities. Therefore, we investigated joint endoprosthesis infections in Germany (2005-2012) focusing on elderly patients. We extrapolated infection related costs to estimate the burden for the health care system.

Laboratory bioassays were conducted in Calabar, Nigeria, to evaluate repellencies of the essential oils extracted from Xylopia aethiopica and Dennittia tripetala fruits, chemical constituents of the oils and their blends as well as compare repellencies of the blends with those of the constituents using a 3-day old adult Prostephanus truncatus, a primary pest of stored maize and dried cassava chips, cultured in the laboratory. Fresh fruits of X. aethiopica and D. tripetala, 100 g each was collected, washed and dried, then pounded separately using laboratory pestle and mortar for the extraction of essential oils

Dental carries is a disease with both high prevalence and severity in adults’ worldwide population. Dental carries affect over half of the population in both developed and developing countries globally. Since the outcomes from dental carries are mostly discrete, they are often modelled using count regression models. It is therefore the purpose of this study to determine the appropriate count regression model that efficiently fits the Decayed Mining and Filled Teeth Data (DMFTDATA) and further identify the key risk factors contributing significantly to dental carries in adults in Ghana using the appropriate count regression model.

We propose a novel strategy to predict unknown data from a smaller sample size by using compressive sensing which is one of the information technology used in artificial intelligence. In this study, we applied the compressive sensing to an empirical sample of clinical trials comprising of two groups. Each group required the time data of 25 patients but the data of 12 more patients had to be acquired to satisfy alpha and beta errors.

Celiac disease (CD) is a systemic chronic immune-mediated disorder that is associated with weight loss, diarrhea, and laboratory abnormalities. Celiac disease (CD) is a disease in which the mucosal lining of the small intestine is damaged in response to the ingestion of gluten and similar proteins, which are found in wheat, oats, rye, barley and other grains. Children with CD are very common [1].

Xeroderma Pigmentosum (XP) is a rare autosomal recessive disorder characterized by an extreme sensitivity to UV rays from sunlight, a high incidence of skin cancer and occasional neurological symptoms. XP, primarily defined as a DNA repair syndrome, has been found associated with defects in the Nucleotide Excision Repair (NER) pathway, and more recently by transcriptional deregulation. XP results from mutations in eight genes (XPA to XPG and XPV) coding for proteins involved in NER.

Malnutrition remains a concern in the central province, despite being the most productive province in terms of Agriculture. Most studies in the province have not paid attention to the importance of women empowerment and the nutrition outcomes of the population. In light of this knowledge gap, this study focused on the Women’s empowerment and the nutrition status of children aged 6-59 months.

This work presents the first record of the regular sea urchin Sphaerechinus granularis in a coastal lagoon in the Mediterranean. S. granularis (Echinoidea: Echinodermata) was found for the first time in Bizerte lagoon (North Western Tunisia) associated with a population of the sea urchin Paracentrotus lividus at 5,5 m deep and on sandy mud substratum with Cymodocea nodosa beds. This finding demonstrates that the species can live in a semi enclosed Mediterranean ecosystem where the environmental conditions (i.e. temperature and salinity) are very variable.