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Articles Related to HP

Formulation and In-vitro Characterization of Fluoxetine Hydrochloride Loaded Fast Dissolving Oral Film Using HPMC 15CPS and HPMC K4M

Fluoxetine Hydrochloride (FH), a selective serotonin reuptake inhibitor (SSRI) is a drug of choice in depression, obsessive-compulsive disorder (OCD), bulimia nervosa, etc. Though tablet, capsules, oral solution, or syrup are currently available conventional dosage form of FH, modified or immediate-release formulations for fast onset of action is of utmost importance.
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Formulation and Characterization of Diclofenac Potassium Transdermal Patches Prepared with Ficus auriculata Fruit Mucilage and Hydroxypropyl Methyl Cellulose K4M

The delivery of the drug at a predetermined controlled rate and its systemic effect is utmost important. Topically administered medicaments in the form of patches is being popular for its effectiveness. The main objective of this research was to formulate matrix-moderated transdermal patch of diclofenac potassium and to evaluate them concerning various in-vitro parameters.
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A Simple Method for the Quantification of Atenolol from the Forensic Human Blood and Visceral Samples by High Performance Thin Layer Chromatography

A simple High-Performance Thin layer chromatography (HPTLC) method has been developed for determination of atenolol in human blood and viscera. The mobile phase was ethyl acetate, acetone, ethyl alcohol, ammonia solution in the ratio of 45:45:7:3. The densitometry scanning at 254 nm was found to be maximum absorption for standard atenolol. The standard and extracted atenolol from samples were detected by HPTLC and confirmed with authenticated spectra at 254 nm. The quantity of the atenolol determined to be 1.6 µg for viscera and 1.5 µg for blood sample.
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Separation and Detection of Monocrotophos by Chromatography Methods in Forensic Samples

Monocrotophos is a extremely hazardous organophosphate insecticide that is extensively used and easily accessible in India.
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Determination of N-Butylscopolamine in Human Plasma by Solid-Phase Extraction and UHPLC-ESI-MS/MS: Development, Validation and Application to a Bioequivalence Study

BioequivalenceA sensitive ultra performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS) method for measurements of N-butylscopolamine in plasma was developed and validated. A SPE extraction was proposed for the clean up of plasma and N-butylscopolamine-d9 was added as internal standard. The analyses were carried out using a phenyl column and mobile phase of acetonitrile:
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A Study on Chromatography Methods for the Separation and Detection of Certain Benzodiazepine Drug in Forensic Sample

Forensic Scientists are required to identify an ever increasing and more complex assortment of drugs and related compounds.
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Optimization of Pseudomonas aeruginosa for Chlorpyrifos Degradation using Response Surface Methodology

Chlorpyrifos is a hazardous organophosphate pesticide used worldwide thus its biodegradation is need of the time. In the present study 13 bacterial strains were isolated from collected soil samples of different agro climatic regions and out of them one bacterial strain was screened out as potent degrader of Chlorpyrifos on the basis of percentage degradation using high pressure liquid chromatography (HPLC).
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A Young Woman with Abdominal Pain: Unintentional Toothpick Ingestion

Foreign body ingestion is a common occurrence among children and adults with certain risk factors including advanced age and psychiatric diseases. However, in clinical practice we encounter healthy adults who are diagnosed with unintentional foreign body ingestion and are not able to remember it. These cases may be complicated by gastrointestinal perforations in case of ingesting sharp objects. Only clinical suspicion would help clinicians for prompt diagnosis in such cases.
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Targeted Killing of Streptococcus mutans in Biofilms by a Pheromone Guided Antimicrobial Peptide HP30

Streptococcus mutans is a leading cariogenic pathogen of dental caries worldwide. Clinically, eliminating S. mutans from dental biofilms using antibiotics is not practical, because these agents indiscriminately kill other members of the resident flora, leading to ecological disruption and other negative clinical consequences. To develop target-specific antimicrobials, we evaluated several fusion peptides and identified a new peptide HP30 that showed a high selectivity for targeted killing of S. mutans.
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Novel analytical technologies of Quality in the Sheep & Goat Dairy Sector

France, Greece, Italy, and Spain the major sheep and goat milk producers in Europe, got the initiative through an interim of 30 years (1985 – 2015), to organize - through IDF - 7 symposiums aiming at the upgrade of the Dairy Sector. One major interest was the milk quality. Stepwise, the efforts followed cow milk structural development in organizing the testing laboratory, the definition of quality in composition (fat, protein, lactose, total solids), in Hygienic (Total Bacteria Count, Somatic Cell Count, antibiotics residues and Aflatoxin M1 contamination), adulteration with water and detection of milk species. EU, by Decision 2002/657/EC, defined the rules for the Directive 96/23/EC, enumerated the testing methods, the demands in sampling procedures, the minimum limits of performance, the quality control (ISO 17025) and the interpretation of results. The equivalency of results from different laboratories, through ISO 17025, demanded the application of ISO analytical standards.
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Awareness of Cervical Cancer Risk Factors, Screening Practices and Attitudes among Nurses in a Primary Health Care Setting of Morocco: A Cross-Sectional Study

The effectiveness of the cervical cancer screening activities depends on physicians and nurses’ level of awareness and their adherence to the program.
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The Impact of Repeated Hb A2 Measurements on β-Thalassemia Trait Diagnosis

Hemoglobin A2 (Hb A2) is a minor component of the hemoglobin present in normal adult red blood cells, accounting for 1.5-3.5% of the total hemoglobin in healthy individuals.
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A One-Year Hospital Based Prospective Study of Sickle Cell Disease from One Capital Area of Kuwait by HPLC

Haemoglobinopathies are inherited disorders of haemoglobin synthesis that are responsible for significant morbidity and mortality all over the world.
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Serum Haptoglobin Responses following Rumenotomy in the Sahel Goat

Fifteen Sahel goats were randomly allocated into three groups A, B and C to evaluate Serum Haptoglobin (Hp) profiles following rumenotomy as markers of surgical stress using Quantitative ELISA.
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Effects of Age and Sex on Sickle Cell Disease Avascular Necrosis

Sickle cell disease (SCD) is a hemoglobinopathy. Based on genotypes, it is classified into sickle cell thalassemia (SCTh) and sickle cell anemia (SCA).
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Editorial Board Members Related to HP

Peter Schemmer

Professor
Department of General -, Visceral- and Transplant Surgery
University Hospital of Heidelberg
Germany

HALEH SANGI-HAGHPEYKAR

Associate Professor
Department of Obstetrics and Gynecology
Baylor College of Medicine
United States

Lisa M Dadio

Lecturer
Department of Forensic science
University of New Haven
USA

Zafar K. Khan

Professor
Department of Microbiology and Immunology
Drexel University
United States

Mahesh Goel MS

Associate Professor
Department of Surgical Oncology
Tata Memorial Hospital
India

Mehmet SOY

Professor
Department of Rheumatology and Internal Medicine
Altinbas University, Bahceievler Medical Park Hospital
Istanbul, Turkey

Sacha A.F.T. van Hijum

Principal Investigator
Radboud university medical center and NIZO food research
Netherlands

Ahmed S. Zidan

Associate Professor
Department of Pharmaceutics and industrial pharmacy
Zagazig University
Egypt

Scott Asbill

Professor of Pharmaceutics
College of Pharmacy & Health Sciences
Campbell University
United States
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