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Diagnosis and Treatment of Atypical Thoracic Outlet Syndrome*

With the progress of society, the development of science and technology, and the popularization of digitalization, the number of patients seeking treatment for "hand numbness" in the outpatient department of rehabilitation medicine is increasing day by day, and it shows a younger age, even some teenagers; Most of them are diagnosed as cervical spondylosis, but according to the treatment of cervical spondylosis, the effect is not good, sometimes prolonged and not cured, which has different degrees of impact on the work and life of patients, and even affects the physical and mental health of patient
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Case Report: Pyoderma Gangrenosum in IBD Treated with Tofacitinib

Pyoderma gangrenosum is a rare ulcerating skin disease often presenting as an extra intestinal manifestation of IBD and is difficult to manage. Treatment options for pyoderma gangrenosum include steroids, calcineurin inhibitors and anti TNF agents. Here in, we report a case of recurrent Pyoderma gangrenosum with Ulcerative Colitis that was successfully managed with Tofacintib, a JAK inhibitor
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The Impact of Exploring Chromosome Philadelphia like on the Prognosis of Children and Teenager ALL

Acute lymphoblastic leukemia (ALL) is considered as the most common pediatric malignancy with 80% of frequency in children between 1 and 10 years old. With the evolution of science, improved diagnosis and adapted treatment, all survival rates increased to a possibility of 80%. Philadelphia chromosome like acute lymphoblastic leukemia (Ph-Like ALL) is a recent genetic discovery characterized by a gene expression profile and high frequency of IKZF1 gene alteration similar to that of BCR-ABL1 positive ALL with a poor outcome.
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Awareness towards Dental and Oral Health among Parents of Children Undergoing Anti-Cancer Treatment

The study aimed to assess the attitudes toward dental and oral health of parents of children receiving anti-cancer treatment. Methods: This cross-sectional descriptive study was based on a convenience sample of parents of 50 pediatric patients who were receiving anti-cancer treatment (study group) and 62 parents of healthy children (control group). Questionnaires were distributed to assess awareness towards oral and dental care.
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Radiomics, PET-PSMA and Machine Learning for Intraprostatic Cancer Diagnosis

Prostate cancer (Pca) is the second most prevalent malignant neoplasia in man, just after non-melanoma skin cancer. Today, prostate biopsy for tissue sampling is still the gold standard for its diagnosis. However, new generation imaging exam has been used in several clinical scenarios. Yet, positron emission tomography (PET) that targets a specific transmembrane protein on prostatic cells
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Superficial CD34-Positive Fibroblastic Tumor: First Case Report from Latin-America and Review of the Literature

Superficial CD34-positive fibroblastic tumor is an infrequent soft-tissue tumor characterized by a lesion located in the subcutaneous fascia without affecting the soft or deep muscle planes. Its incidence is unknown; therefore, it represents a diagnostic challenge for both the surgical oncologist and pathologist. Given its high risk of local recurrence, extensive surgical resection is the recommended treatment modality. This is the first report of this rare entity in Latin-America.
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Does Body Mass Index Influence the Onset and Prognosis of Colorectal Cancer?

Overweight and obesity are considered an increasing colorectal cancer risk factor. The association between excess body weight and colorectal cancer appears to be related to a state of systemic low-grade inflammation, due to an overproduction of proinflammatory cytokines.
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Review on MALDI TOF MS: Modern Disease Diagnosis Approaches in Microbiology and its Mechanism

Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) has become a widely used technique for the rapid, accurate, durable, economical, and trustworthy method for identification of bacteria, mycobacteria and fungal pathogens in the microbiology laboratory.
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Effectiveness of a Brief Diabetes Risk Assessment Instrument for Detecting Undiagnosed Type 2 Diabetes Among High-Risk Ethnic Communities in West Africa

With the growing burden of type 2 diabetes (T2D) and associated health, social, and economiccosts in sub-Saharan Africa, tools are needed to assess T2D risks rapidly, allowing for targeted early intervention. The objective of this study was to assess the effectiveness of a brief diabetes risk assessment instrument for detecting undiagnosed Type 2 Diabetes among high-risk ethnic communities in Benin, West Africa.
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Stroke Mimics: Diagnosis and Management of Patients with Suggestive Clinical Manifestations of Ischemic Stroke

Background and Purpose: Ischemic stroke is a treatable medical emergency. The diagnosis of stroke is mainly clinical and not always so obvious. Intravenous thrombolysis treatment with altepase IV and endovascular treatment have been proved as fist-line beneficial options for eligible patients who have acute ischemic stroke. However, approximately 30% of patients who experience an acute neurological deficit compatible with ischemic stroke fall into the category of "stroke mimics"
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A review on the role of acemannan in the Aloe -based nanostructures

n recent years’ nanostructure materials (NSMs) have been of great interest as catalysts and other applications because of their unique textural and structural characteristics. Out of various biomaterials employed for NPs synthesis, plant extracts have attracted much attention due to their effectiveness, availability, and green characteristics. Due to the range of chemical constituents, currently, the incorporation of the Aloe chemical constituents into other substances makes the biosynthesis of NPs which are very necessary for the formation and applications ofAloe-based NPs
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Prenatal Diagnosis of Hydranencephaly in a Newborn of Psychic Mother with Olanzapine and Paroxetine Exposure During The Pregnancy

Hydranencephaly is an extremely rare congenital anomaly of the central nervous system, characterized by the almost total absence of the bilateral cerebral hemispheres and replaced by cerebrospinal fluid. Almost all cases are sporadic with an incidence of less than 1 per 10,000 births and a very poor prognosis. The exact main cause is still unknown, but hydranencephaly is usually found to develop secondarily to the occlusion of cerebral arteries above the supraclinoid level. We report the case of a full-term female infant with hydranencephaly diagnosed at 28 weeks of gestation by routine antenatal intrauterine ultrasonograph
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An Unexpected Diagnosis of Plasmacytoma of The Thyroid: A Case Report and Review of The Literature

Plasmacytoma is a malignant proliferation of plasma cells that can arise in the bone marrow (osseous) and in the soft tissues. Extramedullary plasmacytomas most commonly occur in the upper respiratory tract. Thyroid involvement is rare. In this report, we describe a new case plasmacytoma of the thyroid gland in a 60-year-old man with a history of multinodular goiter present for several years and an unexpected rapid increase of the mass associated to dysphagia, dyspnea, and dysphonia. Histopathological examination of surgical specimen, along with immunohistochemical studies, unexpectedly led to the diagnosis of plasmacytoma. We also briefly summarize the last 30 years of literature on thyroid plasmacytoma and review the salient characteristics of this rare condition.
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Detection of a Rheumatic Factor (RF,) Anti- Cyclic Citrullinated Peptides (Anti CCP) Antibodies and C- Reactive Protein (CRP) in Diagnosis and Prognosis of Rheumatoid Arthritis

Introduction: Rheumatoid arthritis ( RA)is an autoimmune and inflammatory disease. It is characterized by arthrosynovitis with resultant joint destruction . So, an early clinical diagnosis along with simple serological tests like anti CCP antibodies, C –reactive protein ( CRP) and Rheumatoid factor (RF) play an important role .An attempt was made to study and compare these parameters in OPD and IPD RA patients in our hospital setup, VMMC and Safdarjung Hospital , New Delhi. Aims and Objectives: To study the role of RF , Anti-CCP antibodies and CRP in early detection and prognosis of Rheu- matoid arthritis. Materials and Methods: A Total of 440 samples were studied from January 2018 to December 2020 (3years). Correlation between Rheumatoid factor(RF) ,anti CCP antibodies and CRP in suspected RA patients from various departments like PMR , Orthopaedics , Medicine, Obstetrics and Gynaecology and Paediatrics was attempted. RF and CRP was performed using latex agglutination test and anti CCP antibody by ELISA. Results and Conclusion: Of 440 samples tested, all the factors were positive in 87 patients . Anti CCP and RF alone was seen in 32 patients. RF and CRP positive in 49 patients, RF alone in 22 patients. In 250 patients all the tests were negative. So, Anti CCP along with RF and CRP showed a better positive predictive value in patients of Rheumatoid arthritis. But positivity of these parameters even in patients who lack sign and symptoms also aids in better diagnosis, treatment and prognosis.
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A Diagnostic Dilemma of Pancreatic Adenocarcinoma: The Duct Cut-off Sign

Pancreatic cancer carries one of the worst prognoses in the United States. It is the fourth leading cause of cancer-related death in the United States and second after colorectal cancer in digestive system cancer-related death. Early detection is the key to improving its prognosis. Surgical resection is the only curative treatment, but even after margin-negative resection, the 5-year survival rate is still 30%. The following case presents a fascinating diagnosis of pancreatic cancer. Despite an initial diagnosis of pancreatitis, negative cytology, tumor markers, and imaging suggestive of intraductal papillary mucinous neoplasm (IPMN), this patient underwent surgical resection that later revealed pancreatic adenocarcinoma of the tail. This article highlights certain imaging modalities and characteristics that are essential in the diagnosis of pancreatic adenocarcinoma, in an effort to guide management of similar cases, with hope it leads to better outcomes.
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Introduction to the special issue on ‘Nanostructures by Valve Metal Anodization’

With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.
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Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes

The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Fabrication of Ordered Arrays of Anodic Aluminum Oxide Pores with Interpore Distance Smaller than the Pitch of Nano-pits formed by Ion Beam Etching

We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Synthesis of BaTiO3 Nanowires via Anodic Aluminum Oxide Template Method Assisted by Vacuum-and-Drop Loading

In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.
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Editorial Board Members Related to NOS

Elena Kolomietz

Assistant Professor
Department of Pathology and Lab Medicine
University of Toronto
Canada

XIANGBING MENG

Research Assistant Professor
Department of Obstetrics and Gynecology
University of Iowa Carver College of Medicine
United States

S. Peder Cuneo

Professor
Arizona Veterinary Diagnostic Laboratory
University of Arizona
United States

Fatemeh Baghbani

Faculty of Biomedical Engineering
Amirkabir University of Technology
Iran

Nikolić Dragan M

Faculty of Medicine
University of Belgrade
Serbia

ARIS CHRISTOU

Professor
Department of Materials Science and Engineering
University of Maryland
United States

JON B. SUZUKI

Professor
Department of Periodontology & Oral Implantolog
Temple University
United States

ELENA A. USACHEVA

Assistant Professor
Department of Pathology
University of Chicago Pritzker School of Medicine
United States

Prof. Dr. Alireza Heidari, Ph.D., D.Sc.

Full Distinguished Professor and Academic Tenure of Chemistry. Enrico Fermi Distinguished Chair in Molecular Spectroscopy. Head of Cancer Research Institute (CRI). Director of the Bio Spectroscopy Core Research Laboratory (BCRL) at Faculty of Chemistry, California South University (CSU), Irvine, California, USA. President of the American International Standards Institute (AISI), Irvine, California, USA. Board Member of the World Association of Theoretical and Computational Chemists (WATOC).

Yi Qian

Professor
Biomechanics
Australian School of Advanced Medicine
Macquarie University
Australia
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