Top Links

Articles Related to STI

Occurrences of Dairy Calf Mortality and Morbidity and the Associated Risk Factors in Sululta and its Environs, Central Ethiopia

Calf morbidity and mortality are important causes of economic losses on dairy farms worldwide. A cross-sectional study and clinical observation was conducted from November 2016 to April 2017 with the objective of determining calf morbidity and mortality and to investigate the potential risk factors for mortality and morbidity in Sululta and its environs. A total of 312 respondents engaged in market oriented small holder dairying were interviewed using a structured questionnaire survey about their farm and calf management practices and major calf health problems encountered and diseases that causes mortality. The overall magnitude of morbidity and mortality of calves were 31.0% and 58.37%, respectively. The major calf diseases found were diarrhea (69.34%), pneumonia (16.54%), liver fluke (2.4%), bloat (2.0%), joint ill (2.4%) and other cases (8.04%). Risk factors such as weaning age, breed and awareness of colostrums, feeding of calf and overall farm management were included. In this study 80.3% of calf mortality occurs under age 3 month and 19.42% is above 3 month. Based on laboratory examination, Salmonella and E.coli were detected from diarrheic calves. Salmonella found at rate of 2/29 (3.6%) and E.coli found at only genus level. In conclusion, the magnitude of calf morbidity and mortality found in this study were much higher than economically tolerable level and could greatly affect the productivity of the dairy farms through mainly decreasing the availability of replacement stock and production of milk. It is therefore, suggested that implementation of improved calf and farm management practices and proper environmental protection in the study areas would significantly reduce calf mortality and morbidity.
View complete article: PDF  |  Full-text

Acceptability of Provider-Initiated HIV Testing and Counseling as an Intervention for Prevention of Mother to Child Transmission of HIV and Associated Factors Among Pregnant Women Attending at Public Health Facilities in Harar Town Eastern Ethiopia 2018

Accepting one’s HIV sero-status is a critical first step in preventing mother to child transmission of HIV. HIV counseling and testing provides an entry point to PMTCT services for pregnant women.
View complete article: PDF  |  Full-text

Decision-Making in Mastitis Prevention and Control at Regional, Herd and Individual Levels Based on Epidemiological and Economic Studies

The objective of this review is to describe results of epidemiological and economic studies carried out in Brazil that can assist in the decision making process at the region, herd and individual levels for the prevention and control of bovine mastitis. At regional and herd-levels, we present data from a time series analysis comparing somatic cell counts in herds located in Brazil and in the United States (US), an estimation of the prevalence of contagious mastitis pathogens in a specific population of herds located at the state of Minas Gerais, and finally we report the identification of risk factors for new and chronic intramammary infections within herds located at the state of Santa Catarina. The outcomes of epidemiological studies that support the decision making process at herd- and individual-level are related to the decrease in prevalence of contagious mastitis pathogens in the herd as well as the estimate of the economic impact of mastitis occurrence.
View complete article: PDF  |  Full-text

“What Matters to You?”: Shared Decision Making in the Post-Paternalistic Era of Oral Health

We live in an individualistic age. People can follow who they like on social media, read news that aligns with their preconceived notions of right and wrong, and generally avoid critical engagement with ideas they disagree with or situations that make them uncomfortable. This modern phenomenon has led to quick judgement and rapid recoil when others share ideas or information that challenges the inertia of their beliefs and choices. In a post-expertise culture [1], people simply don’t want to be told what to do. This is a problem for the profession of dentistry, where the prevailing paternalistic norms for the better part of the past 150 years have focused on the dentist as the unilateral authority, with the primary responsibility of promoting oral health through “education” or “counseling” – polite euphemisms for telling people what to do. Despite our growing body of scientific evidence showing we can keep people and their teeth healthy, we have become collectively exasperated that this evidence-based information isn’t enough to change the behaviors necessary to prevent disease. As healthcare providers, we wonder why people have stopped listening (if they ever really did). But stepping back, we only need to think for a minute about our current cultural milieu, where the curation of consensus leaves us unfollowed, and worse, blocked.
View complete article: PDF  |  Full-text

The Effect of Salbutamol Nebul Treatment on Systolic Pulmonary Artery Pressure in Newly Diagnosed Patients with Chronic Obstructive Pulmoner Disease

The occurrence of pulmonary hypertension [PHT] in patients with chronic obstructive pulmoner disease [COPD] usually indicates progression of the disease and poor prognosis. The aim of this study is to investigate the effect of oxygen and bronchodilator treatment on systolic pulmonary artery pressure induced by exertion test in patients with COPD.
View complete article: PDF  |  Full-text

The Incidence and Durability of Compensatory Hypertrophy in Pediatric Patients with Solitary Kidneys

To evaluate the incidence and durability of compensatory hypertrophy with solitary kidneys in the setting of those with multicystic dysplastic kidney or Wilms tumor status post nephrectomy. We conducted a retrospective cohort study of patients with multicystic dysplastic kidney (MCDK) and Wilms tumor (WT). MCDK patients were verified by sonographic findings prenatally. WT patients entered our study at time of nephrectomy. We compared the natural history of hypertrophy between the two cohorts via renal length measurement. We performed linear regression to predict creatinine clearance from renal length after adjusting for age and cohort status (MCDK v. WT).
View complete article: PDF  |  Full-text

An Investigation into the Range of Movement and Forces Involved by the Application of Wrist Flexion Restraint Techniques - Pain Inducing or Not?

Although the use of physical restraint (PR) is accepted, it remains controversial as staff are required to balance professional, ethical and legal tensions between maintaining everyone’s safety, upholding human rights, and minimising harm. One such tension relates to the use of Wrist Flexion Techniques (WFT) used in some health, social care and custodial settings. WFT impose load onto the musculoskeletal structures of the wrist to gain control or compliance from a restrained person, and can result in discomfort, pain, injury, psychological trauma and be detrimental to therapeutic relationships. Current evidence and guidance on WFT are absent with debate existing as to whether WFT can be used without inducing pain. Twenty adults participated in the study. The mean discomfort angle was 90.1° (± 8.6) of flexion with 2.8 Kg (± 1.1) of force, and the mean pain angle was and 98.4° (± 7.9) of flexion with 4.4 Kg (± 1.8) of force, therefore only 8.3° of movement and 1.6 Kg of force separate pain free from pain inducing WFT. Genders did not differ in relation to angle of discomfort or pain. Females experienced discomfort with 1.1Kg less force (p = 0.021) and experienced pain with 1.7Kg less force (p = 0.023). This research challenges the assertion that WFT can exist as non-pain inducing and pain inducing PR techniques since the margin between them may be too small for practitioners to discriminate, particularly during the struggle of real world restraint. Further research may consider other potential pain inducing techniques, and the role and use of PIT during restraint.
View complete article: PDF  |  Full-text

High Glucose Modulates Responsiveness to Estrogens of Human Derived Female Cultured Osteoblasts and in Osteoblastic Cell Lines

Human female- derived osteoblast- like cells in culture (hObs) and the cell lines (SaOS2 and hFOB) express mRNAs involved in bone biology and physiology such as estrogen receptor α (ERα) and α (ERα), vitamin D receptor (VDR), 1α, 25 (OH) vitamin D3 hydroxylase (1OHase) and 12 and 15 lipoxygenases (12LO and 15LO). These mRNAs are modulated by estrogenic compounds. Since the skeletal protective effects of estrogens are not discernible in diabetic women, we tested the estrogenic modulations of these parameters in cells grown in growth medium containing high glucose (HG; 9.0g/L; 44mM) compared to normal glucose (NG; 4.5g/L; 22mM). HG significantly increased DNA synthesis (DNA) and creatine kinase specific activity (CK). Stimulations of DNA but not of CK by estradiol-17β (E2), by 4, 4’, 4’’-[4-propyl-(1H)-pyrazol-1, 3, 5- triyl] tris-phenol (PPT; ERa specific agonist), or by 2, 3-bis (4-hydroxyphenyl)-propionitrile (DPN; ER β specific agonist), were modulated by HG. HG Itself up regulated the expression of mRNA of 12LO and 15LO and to less extent ERβ and VDR, but had no effect on ERα and 1OHase mRNA expression. The different hormonal treatments modulated the expressions of VDR, 1OHase, 12LO and 15LO mRNAs which were reduced in HG, whereas the induction of their products 1α, 25 dihydroxy-vitamin D3 (1,25D) and 12- and 15- hydroxyeicosatetraenoic acid (12 and 15 HETE) were only slightly affected by HG. The exact mechanism of HG effects on bone cell responses and its relationship to human bone physiology is not yet clear.
View complete article: PDF  |  Full-text

Relationship between Insight, Self-Stigma and Level of Hope among Patients with Schizophrenia

View complete article: PDF  |  Full-text

Current Trends and Risks of Autism and Vaccine Delivery

Autism Spectrum Disorders (ASD) is regular heterogeneous neurodevelopmental disorder with symptoms like disability in social association, repetitive behavior interest and activities. Etiology of autism and different speculations of ASD were proposed keeping in mind the end goal to clarify the pathophysiology of ASD.
View complete article: PDF  |  Full-text

Clinical and Paraclinical Profile of Patients in First Nephrology Consultation at the Aristide Le Dantec University Hospital Center (ALD-UHC) About 542 Cases

Late recourse to nephrology consultation remains a topical issue which concerns both developed and developing countries such that a majority of the patients are seen to be at an advanced stage of chronic kidney diseases. The aim of this study is to assess the clinical and paraclinical profile of patients referred for primary nephrological consultation.
View complete article: PDF  |  Full-text

Preliminary Investigation of the Interaction of Misoprostol and Phenylbutazone on Bone Response to Injury in Horses

Phenylbutazone (PBZ) is commonly used in equine patients for treatment of orthopedic injuries. Phenylbutazone may adversely affect bone healing because of suppression of prostaglandin production. We hypothesized that administration of the prostaglandin analog misoprostol would enhance bone healing and mitigate the untoward effects of PBZ on bone response to injury in horses. The objectives of this study were to determine whether the administration of misoprostol would enhance bone healing and whether concurrent administration of PBZ and misoprostol would mitigate the untoward effects of phenylbutazone. Twenty horses were randomly assigned to one of four groups (n=5 per group): Group 1 (untreated control), Group 2 (phenylbutazone alone), Group 3 (misoprostol, alone), or Group 4 (concurrent treatment with phenylbutazone and misoprostol). A 4.5-mm diameter uni-cortical bone defect was created in one metacarpal III bone of all horses. Fluorochromic bone labels were administered intravenously on Days 0, 7, and 14. Computed tomographic osteoabsorptiometry and histomorphometric analyses were performed on the harvested metacarpal bones. Phenylbutazone treatment caused a decrease in endosteal new bone formation. Administration of misoprostol appeared to mitigate the magnitude of the PBZ effect on new bone formation (endosteal in-growth, p<0.06). Bone specific alkaline phosphatase serum activity decreased throughout the 14-day period of stall confinement. Mineral apposition rates increased in all groups during the period from 7 to 14 days after bone injury. Further research is needed to determine if this effect is significant. The administration of misoprostol may be beneficial to lessen the undesired impact of phenylbutazone on bone healing in horses.
View complete article: PDF  |  Full-text

A Traumatic Context Can Hide a Sexual Rape

Aeric syndrome during a multiple trauma reflects the severity of this latter, which made mention to extra thoracic or intra thoracic lesion. This requires a good diagnostic and therapeutic strategy. We report the case of a young patient admitted to emergency in an array of closed multiple traumas where the etiological diagnosis was rare and unknown. This case highlights that a careful questioning and a good examination in admission can reveal earlier the diagnosis, the thing that was not well led in our case, because the patient was mute, anxious, and not cooperating making unnoticed rape history.
View complete article: PDF  |  Full-text

Using Simulation and Data Mining For Engineering Knowledge Improvement

Significant work has been attempted to better comprehend the attributes and mechanisms suggested in simulation and data mining in precedent research. More prominent understanding causes not only give progresses in numerous fields but also enable experts to better consider the last target.
View complete article: PDF  |  Full-text

An Insight into the Role of Spliceosomal Mutations in Myelodysplastic Syndromes

The identification of altered splicing signatures in Myelodysplastic Syndromes (MDS) could likely provide key markers for diagnosis, prognostication and development of novel therapeutics. This review presents an insight into role of spliceosomal gene mutations in the pathogenesis of MDS, emphasizing on their clinical and prognostic significance. We also discuss emerging studies delineating the functional consequences of these mutations and pointing towards the emergence of a new leukemogenic pathway involving spliceosomal dysfunction.
View complete article: PDF  |  Full-text

Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
View complete article: PDF  |  Full-text

Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
View complete article: PDF  |  Full-text

Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
View complete article: PDF  |  Full-text


Editorial Board Members Related to STI

Wen-Quan Zou

Associate Professor
Departments of Pathology and Neurology
Case Western Reserve University School of Medicine
United States

Magdolna Csavas

Associate Professor
Department of Pharmaceutical Chemistry, Faculty of Pharmacy
University of Debrecen
Hungary

Simone Maurea

Associate Professor
Diagnostic Imaging
University Federico
Italy

Guoshun Wang

Associate Professor
Departments of Microbiology and Immunology, Genetics, and Medicine
Louisiana State University Health Sciences Center
United States

Adriana Estokova

Head of Department of Material Engineering
Faculty of Civil Engineering
Institute of Environmental Engineering
Slovakia

Jane F Manakil

Professor
Department of Dentistry and Oral Health
Griffith University
Australia

Will Xia

Assistant Professor
Department of Biological Sciences
Wichita State University
United States

Meijun Zhu

Assistant Professor
School of Food Science
Washington State University
United States

Panagiotis A. Eliopoulos

Associate Professor of Agricultural Entomology
School of Agriculture
Department of Agricultural Technologists
Greece

Kwang-Hyun Baek

Department of Biomedical Science
CHA University
Republic of Korea
Submit Manuscript