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To identify pathogens that are frequently isolated from wound infections in the Turks and Caicos Islands and formulate antibiogram based on their patterns of antimicrobial susceptibility. Bacteriology and antimicrobial susceptibility data from 1343 wound swabs cultured at the Cheshire Hall Medical Laboratory between January 2013 and November 2015 were retrospectively analyzed. The Kirby-Bauer disc diffusion technique was used to perform antimicrobial susceptibility testing. 79.1% of the 1343 swabs cultured were positive yielding a total of 1687 bacterial isolates. Frequently isolated bacteria included Staphylococcus aureus which accounted for 27.6% of isolates, approximately a third of which were methicillin resistant, Pseudomonas spp. (12.1%), Proteus spp. (8.2%), Enterococcus spp. (7.8%), E. coli (7.2%), Streptococcus agalactiae (6.1%), Klebsiella spp. (5.5%), Acinetobacter spp. (4.3%), coagulase negative Staphyloccus (4.0%) and Enterobacter spp. (3.7%). The overall highest resistance rates were seen among tetracycline (46.3%), erythromycin (37.6%) and ceftriaxone (34.2%). Imipenem, penicillin, meropenem and vancomycin had sensitivity rates ranging from 92.3% to 99.5%. Individual resistance rates varied among isolates, some differing significantly from overall rates. When tested against antibiotics routinely used to treat Pseudomonas spp., resistance rates ranged from 1.4-55.5%.

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Interferon-gamma (IFN-γ) is associated with the inflammatory responses modulation, which could culminate in chronic metabolic diseases. In this context, the aim of the present study was to evaluate the effect of the acai (Euterpe oleracea Mart. mart.) pulp consumption on the anthropometric, clinical and biochemical parameters in women clinically healthy, with IFN-γ, respectively, smaller and higher than 5 pg/mL. Twenty four women in G1 (with IFN-γ concentrations smaller than 5 pg/mL) and sixteen in G2 (with IFN-γ concentrations greater than 5 pg / mL), consumed 200g per day of acai pulp during four weeks. Anthropometric and body composition measurements, biochemical and clinical data were evaluated before and after the intervention

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Correlation formulas are developed to estimate the dietary and total greenhouse gas emissions (GHGEs) from Group of Twenty (G20) and the world in 2014 and 2017 using personal meat consumption as the required input. Among the 43 states involved in G20, the 28 states of the European Union (EU28) are considered as a whole. Based on 47,381 dietary survey samples, a formula is developed to establish the relationship between the meat consumption and GHGEs from human dietary and total activities.

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Vascular variations of the head and neck are common, but oft en go unnoticed because they generally do not present clear clinical symptoms. Lack of awareness of the presence and location of such variations may result in iatrogenic complications or even fatalities. Physicians and surgeons should be cognizant of such variations given their potential clinical signifi cance.

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The mental health as field of action for the physiotherapists is an important challenge that implies formation and investigation. The alterations of the mental health on a global scale are nowadays a problem of public health that it makes necessary that the professionals of the area of the health have a deeper knowledge on the topic to act of way adapted from the prevention and intervention.

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Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disease. Several indexes can measure SLE activity, and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) is one of them. The aim was to associate SLEDAI with inflammatory biomarkers present in serum (C3, C4, CH50, C-reactive protein, and creatinine), proteinuria (urine 24h) and urine NGAL in SLE patients. This study included 43 SLE patients who were arranged in two groups according to the value of SLEDAI. One group, SLEDAI 0-4 (n=25), included SLE patients with low activity, and the other group, SLEDAI >4 (n=18), included SLE patients form moderate to high activity. Level of urine NGAL (uNGAL) was determined by ELISA, and the data were analyzed using GraphPad Prism 5.

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The identification of altered splicing signatures in Myelodysplastic Syndromes (MDS) could likely provide key markers for diagnosis, prognostication and development of novel therapeutics. This review presents an insight into role of spliceosomal gene mutations in the pathogenesis of MDS, emphasizing on their clinical and prognostic significance. We also discuss emerging studies delineating the functional consequences of these mutations and pointing towards the emergence of a new leukemogenic pathway involving spliceosomal dysfunction.

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Attribution of etiology for disease syndromes is critical to guide appropriate public health interventions. Partial latent class analysis model (pLCM) methods have recently been developed to address this area of research; however, model parameters, assumptions, and performance are not well understood for the general etiology problem.

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A sixty-year-old woman with no remarkable systemic disease came to our clinic due to blurred vision of right eye for one month. The best corrected visual acuity (BCVA) was 0.2 in the right eye, while intraocular pressure, anterior segment, and optic disc of right eye were all normal. Optical coherence tomography (OCT) was arranged, which showed VMT in right eye.

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Bioavailability in different formulations of desvenlafaxine100 mg prolonged-release tablets was compared in two bioequivalence studies, one under fasting conditions and the other after a standard breakfast. Both studies were a single dose, randomized, open-label, two-period crossover, with Brazilian male and female healthy subjects. Blood samples were taken during 48 h and plasmatic concentrations were determined using a validated UPLC-MS/MS method.

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The de-extinction of the dinosaur is a dubious possibility but its consideration brings forth some issues that are at least worthy of scientific discussion. In this review, we discuss two distinct issues that have implications for a de-extinct species such as a dinosaur: the ability, or lack thereof, to safely sedate a rare and potentially fractious animal capable of harming the veterinary staff tasked with its care; and, disease risks associated with a species that has been extinct for millions of years. To identify potential sedatives, comparative pharmacology will be needed to uncover the links between receptor pharmacology and the desired clinical outcomes of activating established alpha-2 adrenergic, opioid, and benzodiazepine receptors. Specific to disease control, it will be necessary to understand the unique susceptibility of the new species to current diseases as well as predicting their reservoir capacity for potential human and veterinary pandemic diseases. While the topics presented herein are not exhaustive, this review highlights some of the foremost research that should be conducted in order to serve the unique veterinary needs of a de-extinct species using the dinosaur as a paradigm. Addressing these issues should be considered if an intact dinosaur genome becomes available, regardless of the feasibility of dinosaur resurrection.

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Pressure head was gained from the distribution of pores to characterize the sandstones of the Shajara reservoirs of the permo-Carboniferous Shajara Formation. The attained values of pressure head were employed to calculate the pressure head fractal dimension. Based on field observations in addition to the acquired values of the pressure head fractal dimension, the sandstones of Shajara reservoirs were divided here into three units. The obtained units from base to top are: Lower Shajara Pressure Head Fractal Dimension Unit, Middle Shajara Pressure Head Fractal Dimension Unit and Upper Shajara Pressure Head Fractal Dimension Unit.

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Cerebral amyloid angiopathy (CAA) is frequently associated to Alzheimer’s disease (AD) but can also occur in Lewy body dementia (LBD). The present post-mortem study compares the incidence and the topographic distribution of small cerebrovascular lesions in LBD brains without and with severe CAA (LBD-CAA).

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A field experiment was conducted at Farmer’s field in Banepa, Kavreplanchowk District during the spring season, 2015 to find out the optimum plant spacing on cauliflower production. Four plant spacing viz. (i) 45×45 cm in single row spacing, (ii) 52.5×45 cm in double row spacing, (iii) 52.5×30 cm single row spacing and iv) 52.5×30 cm in double row spacing were included in the study

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The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.

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Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.

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The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.

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Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.

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