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The articular cartilage overlying the bone consists of a network of collagen fibres. This network is essential to cartilage integrity, usually suffering damage in degenerative joint diseases such as osteoarthritis. We have been applying a number of techniques to study the bone-cartilage interface and of changes occurring in this with disease. The bone-cartilage samples with disease were investigated for their structural, elemental and molecular properties. The bone-cartilage samples with disease were characterized by scanning electron microscopy- energy dispersive X-ray spectroscopy (SEM-EDX) and Fourier Transform infrared spectroscopy (FTIR) and Fourier transform (FT) Raman spectroscopy.

Diabetes poses many unique challenges to all individuals affected by the disease, particularly the diabetic athlete due to the effect that exercise has on blood glucose levels within the body. Patients and professionals must demonstrate significant understanding of the complex interaction of many physiological and environmental components that contribute to the maintenance of glucose homeostasis, or lack thereof. Type 1 Diabetes Mellitus is the form of Diabetes most often seen in elite athletes.

Objective: To evaluate the functional mobility of chronic hemiparesis sufferers who undergo 12 weeks of GPCT. IntroductionMethod: We selected 10 chronic hemiparetic patients, aged 21 or over with a medical referral and one-sided hemiparesis with an injury time of ≥12months, capable of walking with or without help and having the ability to perform walking tests. Interviews to collect personal data were conducted, which were then evaluated by Time up & go (TUG) which recorded the time taken for the patient to stand up from a chair, walk 3 meters, return and sit constituting the initial assessment (AV1) and after 12 weeks of intervention with GPCT the final evaluations were taken (AV2).

Myasthenia gravis is an autoimmune disease characterized by motor plaque dysfunction due to antibodies against post-synaptic membrane proteins. Myasthenic symptoms classically wax and wane and are more intense at the end of the day, although they may be constant in severe pictures. Almost every patient have eyelid ptosis and double vision, and the majority of them also have proximal muscle weakness. Reversible cholinesterase inhibitors are the first-line treatment, but patients who do not achieve symptom control should receive immunosuppressive therapy, whose options include azathioprine, cyclosporine, mycophenolate, intravenous immunoglobulin and thymectomy, with different profiles of efficacy, safety and tolerability.

To report outcomes after vitrectomy with ILM peel for bilateral elevated foveoschisis in a patient with Goldmann-Favre syndrome. Vitrectomy with ILM peel was done for one then the other eye of a 19 year-old patient with bilateral progressive enhanced s-cone syndrome associated elevated macular retinoschesis. Significant anatomical as well as visual improvements were noted in both eyes with regression of the macular edema, flattening of the retinoschesis, and a stable visual outcome thereafter. Despite the Inherent Risks of Surgery, Vitrectomy with ILM Peel may provide a possible surgical treatment option for patients with elevated retinal foveoschisis associated with enhanced S-cone syndrome.

Infective endocarditis (IE) is a serious infectious disease that carries a high mortality rate. We report the case of 74-year-old female who is a chronic hemodialysis patient, and was presented with tricuspid valve endocarditis (TVIE) with central venous catheter, due to an Enterobacter Cloacae, which is a non-HACEK Gram-negative bacilli (GNB) and has been reported to be an extremely rare pathogen of IE. The patient was treated with imipenem and teicoplanin for a four-week period, with negative Blood culture and normal C reactive protein (CRP) levels at the end. The aim of our study is to understand the pathophysiology of the IE in chronic renal failure (CRF) especially at the tricuspid valve (TV), and to determine the clinical, biological characteristics and therapeutic modalities.

We investigated the histopathological changes observed in the brains, organs, and apoptotic changes in the brain of young rats born from rats with torsio uteri that survive. We divided 10 Sprague-Dawley rats with a gestational age of 18-19 days into two groups. The rats in group 1 (i.e., the control group; n=5) were given anesthesia only; the rats in group 2 (study group; n=5) underwent a 360-degree clockwise torsion in their uterus, and the torsion was corrected after 6 hours. The births of the offspring were followed, and 7 female and male offspring 1 month of age were selected in each group. The vaginal openings of the young female offspring were checked to determine the time to reach puberty. The 1-month-old male offspring and the mature young female rats were then decapitated. Tissue samples, including visceral organs, genital organs, and brains, were evaluated by histapathologically; we also investigated apoptosis via the TUNEL method. Although no abortion was observed in any of the pregnant rats in the control group, two abortions were observed in the study group after torsion/detorsion.

This study was undertaken to evaluate the influence of levamisole on the immune enhancement of Nile tilapia (Oreochromis niloticus) against potential bacterial pathogens, Fish with weight of 98±5 g were randomly distributed into seven groups each at a rate of 20 fish per 300-L aquarium and fed on a diet containing 0.0, 250, 500, 750, 1000, 1250 or 1500 mg levamisole/kg diet for eight weeks.

In animal production, antibiotics are used at sub-therapeutic and therapeutic levels for growth promotion and disease prevention. Using antibiotics can result in selecting for drug resistant microorganisms that may spread to humans through consumption of contaminated food. Lately, an increased interest in organic farming, where animals are grown without antibiotics, has been popular amongst the consumers. It is believed that organic farming will reduce antimicrobial resistance in microorganisms. However, the animals grown organically may be prone to diseases, and other microorganisms may thrive in the gut, that may be potentially harmful to humans. We analyzed the DNA of fecal samples of pigs grown under conventional and organic dietary regimens and detected the presence of genes that causes antibiotic resistance.

Streptococcus mutans is a leading cariogenic pathogen of dental caries worldwide. Clinically, eliminating S. mutans from dental biofilms using antibiotics is not practical, because these agents indiscriminately kill other members of the resident flora, leading to ecological disruption and other negative clinical consequences. To develop target-specific antimicrobials, we evaluated several fusion peptides and identified a new peptide HP30 that showed a high selectivity for targeted killing of S. mutans.

A cross- sectional study was conducted to assess the nutritional status of the children with rickets aged

Every animal hosts large number of microorganisms most of which affect its body positively. Such positive effect is induced by probiotics, live microbial food ingredients that alter the enteric microflora and have a beneficial effect on the health of an animal. There are many different varieties of friendly bacteria that exist naturally in foods or drinks, or can be added to foods or beverages to enhance health and wellbeing of animals. Thermal treatment and aseptic production of food strongly reduces the amount of microorganisms taken up. This alters the microbial composition in our digestive system.

Fruit and vegetable (F&V) consumption is an important dietary component of disease prevention. Adults who consume more F&V are less likely to develop heart disease, diabetes, and certain types of cancer and are more likely to sustain a healthy weight. In the United States, substantial socioeconomic disparities exist in the prevalence of chronic diseases and the higher prevalence of unhealthy behaviors in lower socioeconomic groups help drive these disparities.

Marchiafava-Bignami disease (MBD) is a neurological disorder that has been found to be associated with chronic alcoholism and malnutrition. We report a 45 year old man, chronic alcoholic that developed discouragement for activities involving daily living, changes in retrograde memory in addition to mutism and gait instability. Brain MRI showed central atrophy of the corpus callosum(CC), hypointensity(necrosis) and ventricular dilation(white matter and subcortical region involvement).

In their first full report on the analysis of GSR by SEM-EDS, Wolten and colleagues stated that the great majority of the gunshot residue particles (GSR), between 70 to 100%, have a characteristic morphology thus providing a detection criterion holding significance equal to that provided by the elemental composition. In fact, the particles must have a spherical or spheroidal shape and their surface should appear amorphous, devoid of any crystalline characteristic.

Background: History of forensic mental health services provide knowledge regarding its evolution that has undergone tremendous changes over the past two centuries. Aim: To study the forensic mental health services and management of psychiatric patients during pre-independence era. Settings and Design: Retrospective, hospital based chart-review and descriptive study. Methods and Materials: Medical records of 85 cases preserved with the 170-year old psychiatric institute were retrieved to study the variables related to socio-demographic characteristics, family background, clinical profile, treatment methods, admission-discharge procedures, and mortality by retrospective chart-review method. Data was analysed using descriptive statistical measures with significance of P

Autonomic nervous system involvement in subjects practicing Yoga has rarely been studied and has shown conflicting results. Our main purpose was to assess the effect of Yoga on autonomic function of group of subjects practicing Yoga regularly in comparison with another group with normal control subjects by measuring the frequency gain response of the two groups. Other aim of this study was to determine wither the duration of Yoga practicing correlated with measures of heart rate variability signal (HRV) using approximate entropy index (ApEn).

To compare three different types of volumetric modulated arc therapy (VMAT) planning techniques using Elekta Versa HD lineer accelerator to deliver total body irradiation (TBI) treatment on the coach and to evaluate the feasibility of VMAT planning technique for TBI treatment.

Acute myeloid leukemia (AML) is a heterogeneous disease. Therefore, various parameters are needed to classify this disease into subtypes. The commonly used method for diagnosis and classification is based on FAB criteria using morphology and cytochemical stains. For some of the categories, immunopheno typing is necessary. The aim of present study is to determine the frequency of various sub-types in acute myeloid leukemia using FAB criteria in our Sudanese population. This will aid in the correct diagnosis of acute leukemia and hence proper management of the patients.

NanotechnologyAbstractIntroductionGraphene has emerged as a potential material in various scientific disciplines, ranging from material science, engineering, and more recently biomedicine. The paper describes the investigation of the presence of graphene and graphene oxide (GO) in the carbon soot of internal combustion diesel engines. The UV-Visible, Fourier transform infrared (FTIR), X- ray diffraction (XRD), Photoluminescent (PL) and Raman spectroscopic analysis of the sample provided a conclusive evidence of the formation of graphene and GO. The Field Emission Scanning Electron Microscopy (FESEM) and Energy Dispersive Spectrum (EDX) of the sample show carbon nanoparticles (CNPs) of size less than 50nm.