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Approach to and Management of a Adynamic Bone Disease in Hemodialysis Patients-A Review

Chronic kidney disease (CKD) is now a global public health epidemic with increasing rates reported all over the world. Currently, more than 850 million people are estimated to live with CKD worldwide. Bone and mineral disorders (CKD-MBD) form an integral part of the management of CKD patients. CKD-MBD encompasses distinct abnormal pathology within the spectrum of Renal Osteodystrophy (ROD), including osteitis fibrosa cystica, osteomalacia, adynamic bone disease (ABD), mixed lesions, and osteoporosis. ABD is primarily characterized by decreased or absent bone formations along with low cellularity of both osteoblasts and osteoclasts as well as thin osteoid seams and minimal or absent peri trabecular/marrow fibrosis. ADB is also associated with a greater risk of vascular calcification and fractures negatively affecting patient outcomes. It is unclear if all forms of ABD are truly pathological or milder forms of ADB could be a compensatory mechanism to guard against bone loss. In this article, we describe a hemodialysis patient profile of ADB with a review of this entity
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Omicron SARS-CoV-2: The Newest Variant

SARS-CoV-2 evolution has undergone several mutations since its initial emergence in late 2019. Successive mutations are a common characteristic of RNA viruses like coronavirus. The emergence of new variants is a result of mutations that differ in their characteristics such as their infectiousness and mortality. Several variants of concern have been identified since the start of the pandemic, including Alpha, Beta, Gamma, Delta, and Omicron. Each of these variants showed unique mutations that raised concerns about their transmission rate, disease severity, and vaccine efficacy. The omicron variant (XBB 1.6), also known as B.1.1.529, attracted significant attention due to its high number of mutations, particularly in the spike protein. These mutations have raised concerns about potential impacts on vaccine efficacy and their ability to evade immunity.
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Characterizations of Cu2FeSnSe4 Thin Films Synthesized from Nanoparticles Powder

Cu2FeSnSe4 (CFTSe) thin film were synthesized on glass substrate by thermal evaporation method at Ts=400° C, starting from elemental powders mixed by a mechanical alloying process. The structural, morphological, compositional, optical and electrical properties of CFTSe semiconductor have been investigated by X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDAX), spectroscopic ellipsometry (SE) and Van Der Pauw technique, respectiv
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Comprehensive Study of Various Chemical Samples in Forensic Toxicology: Focus on Urine Sample

Toxicology deals with the measurement and analysis of toxins. It is itself a vast branch of science, though it has several branches and one of these is forensic toxicology. Forensic toxicology is a branch of toxicology that lines up with other disciplines, namely clinical chemistry, postmortem forensic toxicology, human performance toxicology and forensic drug testing, providing medical jurisprudence of adverse effects such as drug abuse, poisoning and death. The key role of forensic toxicology is to identify and analyse the toxin compounds found during adverse events. This review paper aims to draw an idea about the toxin, in the collected biological chemical samples such as urine samples and their effects on their day-to-day life
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On the Self-Organization of Dielectric Barrier Discharges

The present paper contains experimental analysis of the spatiotemporal structure of atmospheric pressure dielectric barrier discharge (DBD) in a packet-pulse excitation mode widely used as an effective tool for plasma modification of various media. The motivation is the need to optimize the conditions for DBD plasma obtaining with a homogeneous diffuse structure. It is shown that for a discharge gap of the millimeter range (1–3 mm) in atmospheric air, under certain conditions, a number of new plasma phenomena are possible - the effects of an increase in the density (total number) of filamentary discharges over time, both unchanged and with a decrease in the area of the filaments, as well as the formation of complex space-time structures. An interpretation of this phenomenon is proposed. Homogeneous diffuse discharges are obtained in a standard electrode configuration with a single dielectric
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Pulmonary Congestion Dynamics According to Inter-Dialytic Intervals in Hemodialysis

Lung ultrasound (LUS) is reliable in detecting and quantifying of pulmonary congestion in hemodialysis (HD) patients. Pulmonary congestion holds a negative prognostic value in HD patients even when it is asymptomatic. The pathophysiology of pulmonary congestion in HD is complex and includes volume and non-volume dependant factors. We examined the impact of different inter-dialytic intervals on pulmonary congestion by studying its dynamics using lung ultrasou
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Haosmc Growth on Various Sustainable Nano/Micropatterned Surface Topographies Utilising Reusable Surface Templatin

The aim of controlling/regulating cellular processes by surface patterning of biomaterials is a crucial concept in emerging research fields, where the precise fabrication of micro-nano surface topographies is required at manufacturing scales to meet consumer demand. Photolithography is typically employed for surface patterning; however, the high cost, process complexity, and lack of environmentally friendly and sustainable methodologies represent steep barriers for many researchers. Soft lithographic methods have been utilised extensively as a potential alternative for traditional photolithography, yet a photolithographic step is still required for initial template fabrication. Here, we demonstrate the use of repurposed optical consumer items such as DVDs, diffraction glasses, and gratings that would otherwise be thrown away after their useful lives, being used here as a sustainable approach as templates for the formation of complex nano-patterns. By replicating these templates in polydimethylsiloxane (PDMS) and polylactic acid (PLA), we show the varied interactions of human aortic smooth muscle cells (HAoSMC) to these surfaces. Notably, it was demonstrated that, in comparison to nonpatterned substrates, HAoSMC interaction (adhesion, spreading, and viability) was higher on DVD patterned surfaces compared to diffraction glass and grating patterned surfaces according to the results from cell metabolic activity (MTT and Alamar Blue), and proliferation (total DNA) assays. We demonstrate that a simple, reusable, inexpensive, yet robust technology could be a powerful tool in improving our understanding of cell-surface interactions and for the potential development of medical devices with micro- and nanoscale low or high adhesion features
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Theory of Mind Understanding and Socioeconomic Status

The participants underwent assessments across all Theory of Mind (ToM) tasks. All individuals were native speakers, comprising 74 from Iran and 66 from Sweden, aged 6-12, and included those with autism spectrum disorder, Down syndrome, and typical development. We conclude that children’s behavior serves as a scale for social and thought problem assessments, evaluated based on teachers' and parents’ scores.
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The Impact of Seasonal Changes on Growth Performance, Rumen Fermentation, and Rumen Microbiota Structure of Yaks: An Analysis Using the Supplemented 2.5kg Concentrate Level as an Example

The study investigated the effects of supplementing the same level of concentrate in different seasons on the growth performance, rumen fermentation, serum biochemical index, and rumen microflora changes in yaks, to provide guidance on accurate feeding of yaks in cold and warm seasons. 12 healthy yaks weighing (124.21±15.64) kg were selected for the experiment, with a warm season group from August to October and a Cold season supplemental feeding group from October to December. The results showed that the mean daily gain was significantly higher in the warm season grazing group than in the cold season grazing group (p<0.05). Rumen fermentation, serum biochemical index, and rumen microflora changes also varied significantly between the two groups (p<0.05).
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Quantum Quench Dynamics in DNA Molecules at Finite Temperatures

In order to analyze denaturation, we take into account a mapping from the finite temperature phase transition onto a zero temperature quantum phase transition caused by a quench, where the control parameter is the torsion-associated magnetic field and the quench duration handles the temperature effect
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Which Blood Group is More Anemic: Five Years of Retrospective Experience

The relationship between blood groups and diseases has been a subject of interest for many researchers. This study aims to investigate the susceptibility of each blood group to anemia based on the relationship between the erythrocyte indices and the biochemical parameters used to diagnose anemia.
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Explorations of the Combined Effects of Surface Energy, Initial Stress and Nonlocality on the Dynamic Behaviour of Carbon Nanotubes Conveying Fluid Resting on Elastic Foundations in a Thermo-Magnetic Environment

The vibrations of carbon nanotubes under the influences of various internal and external forces have been subjects of interests for some years. These researches have not really considered the effects of surface energy and initial stress which are very important from both material and mechanical aspects of views. Therefore, the current study presents the simultaneous impacts of surface energy, initial stress and nonlocality and other various parameters on the nonlinear vibration of carbon nanotube hot fluid-conveying resting on elastic foundations in a magnetic environment. The derived equations governing the behaviours are solved using Galerkin’s decomposition-Adomian decomposition method is adopted to explore the concurrent impacts of surface elasticity, initial stress, residual surface tension and nonlocality on the nonlinear vibration of singlewalled carbon conveying nanotube resting on linear and nonlinear elastic foundation and operating in a thermo-magnetic environment
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Socio-Economic and Health Status of Rag Pickers in the Dump Site of Mekelle City, Northern Ethiopia

A cross sectional survey on socio economic and health status among randomly selected rag pickers in the dump site of Mekelle city was done during 2020. The study showed that all rag pickers were 19 to 25 years old males; 60% of them were educated up to secondary level
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Comparison of Physicochemical and Binding Properties of Novicel™ Microcrystalline Cellulose and Avicel® PH 101 in Direct Compression of Ascorbic Acid Tablets

Microcrystalline cellulose (MCC) is a key excipient in formulation and production of pharmaceutical solid dosage forms such as tablets. In this study, the microcrystalline cellulose (Novicel™) obtained from sugarcane bagasse (a waste material from sugarcane factories) was compared with Avicel PH 101 (a commercially available MCC) for its physicochemical characteristics and potential as a dry binder in direct compression of ascorbic acid tablets.
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Recurrent Ophthalmic Eczema Herpeticum with Hyper Immunoglobulin E Syndrome in A 4 Years-Old Boy

Eczema herpeticum (EH) is a skin infection caused by the herpes simplex virus (HSV) that occurs in individuals with atopic dermatitis. It is characterized by the sudden appearance of vesicles and erosions with crusts over areas affected by eczema. EH can range from mild and self-limiting in healthy adults to life-threatening in children, infants, and immunocompromised patients. Early treatment with antiviral therapy is crucial in preventing complications and mortality. EH is primarily caused by a superinfection of HSV, usually HSV-1, in individuals with atopic dermatitis. Reactivation of HSV is more common than primary infection. Patients with atopic dermatitis are more susceptible to skin infections due to impaired skin barrier function and immune dysregulation. Disseminated cutaneous HSV infection can also occur in individuals with other forms of dermatitis, known as Kaposi varicelliform eruption (KVE)
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Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes

The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Synthesis of BaTiO3 Nanowires via Anodic Aluminum Oxide Template Method Assisted by Vacuum-and-Drop Loading

In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.
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Editorial Board Members Related to MIC

Nabil Zouari

Professor
Department of Environmental Microbiology
Qatar University
Qatar

Paban K. Dash

Senior scientist
Defence Research & Development Establishment
India

Michael Zhuo Wang

Assistant Professor
Department of Pharmaceutical Chemistry
The University of Kansas
United States

Mamatha Ballal

Professor
Melaka Manipal Medical College
Manipal University
India

Zhenghong Wu

Professor
Department of Pharmaceutics
China Pharmaceutical University
China

TZI BUN NG

Professor of Biochemistry
School of Biomedical Sciences
Chinese University of Hong Kong
China

MICHAEL VAN DOREN JOHNSTON

Professor
Department of Neurology and Pediatrics
Johns Hopkins University School of Medicine
United States

Haider Abdul-Lateef Mousa

Professor
Department of Medical Microbiology
University of Basrah, Iraq
Basrah, Iraq.

LUIS CLAUDIO NASCIMENTO DA SILVA

Department of Parasitary Biology
Ceuma University
Rua dos Castanheiros Jardim Renascença 65075120 - São Luís
Brazil

Jorge Perez

Associate Professor
San Juan Bautista School of Medicine
Caguas
United States
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