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Cognitive-Behavioral Psychotherapy, a Group Psycho-Educational Workshop and a Workshop for Caregivers of Sexually-Abused Children: a Case Study of Two Mexican Male Children

It has been reported that a large percentage of men and women had experiences of sexual abuse during childhood the effects of which are determined by factors such as age, gender, characteristics of the experience, and cultural aspects, among others. In Mexico, only a limited number of sexual abuse cases are reported to the relevant authorities and even fewer receive adequate care and treatment. This article presents an evaluation of the effectiveness of an individualized cognitive-behavioral treatment involving a group psychoeducational workshop and a workshop for caregivers of two Mexican male children who had experienced sexual abuse. Clinical and cognitive evaluations, pre- and post-test treatment, and follow-up one-and-a-half years later were made. Differences between the two participants were found in all three evaluation periods. Various factors associated with these results are discussed.
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Superior Mesenteric Artery Embolus as a Delayed Complication of a Cocaine Induced Myocardial Infarction

Cocaine has acute and chronic effects on health as well as addiction and dependence and places a significant burden on healthcare systems. After cannabis, it is the most frequently used illicit drug worldwide. It is estimated that between 14 and 21 million people use the drug each year [1]. Its main adverse effects occur in the cardiovascular system. Cocaine causes sympathomimetic actions such as tachycardia, hypertension and coronary artery constriction due to enhancement of release of catecholamines. It enhances thrombus formation by activating platelets and potentiating thromboxane production [2]. The consequences of these effects include chest pain, myocardial infarction, aortic dissection, coronary artery aneurysm, myocarditis, cardiomyopathies and arrhythmias. Our case demonstrates a young patient who had a delayed presentation of a myocardial infarction, in the setting of recent cocaine use that was complicated by an apical thrombus which resulted in distal emboli to his superior mesenteric artery and left renal artery. It highlights the fact that in a young patient with no other risk factors how complications may arise, even weeks after cocaine use.
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Endothelial Cells May Have Tissue-Specific Origins

Endothelial heterogeneity reflects many functions performed by endothelial cells (ECs) in various tissues. However, the origin of this heterogeneity is unclear. Here, we report that tissue-specific ECs in lungs, brain, and liver co-expressed the lineage markers of their coordinating tissue-specific cells at very early stages. Specifically, we found that the pulmonary EC population was significantly suppressed after pulmonary epithelial-specific (Nkx2.1-Cre mediated) deletion of fetal liver kinase-1 (Flk1). Together, the results suggest that tissues-specific ECs may originate from the same progenitor cells as tissue-specific cells.
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The Death of a Baby from the Congenital Anomalies of the Urinary Tract

A 36-year-old woman pregnant, G2 P1, presented at 27 weeks of gestation after two previous visits elsewhere, as an outpatient in a gynecological clinic. An ultrasound examination revealed bilateral hydronephrosis. Also, ureteral dilation and bladder overdistension was present (Figure 1, 2 and 3). We evaluated that the cause was a urinary tract obstruction. Specifically, we are dealing with posterior urethral valves. The anteroposterior diameter of the pelvis on a transverse view of the abdomen was 6 mm. The amniotic fluid index (AFI) was 3 cm, so, oligohydramnios. Fetal Biometry responds to the 27th week of gestation. The sex of the fetus was male. Following identification of urinary tract dilation, a detailed anatomic scan was performed to exclude the presence of associated extra-renal anomalies
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Mechanisms of Resistance to Kinase Inhibitors and Strategies to Prevent the Development of Drug Resistance

Targeting mutant proteins and associated signaling pathways of driver oncogenes by small molecule kinase inhibitors (KIs) are a promising strategy of cancer therapy. However, despite the initial success of treatment, KIs often become ineffective as intrinsic and acquired resistance. This article reviews the English-language literature to explore the underlying mechanisms of drug resistance and to present a challenge for developing drugs to overcome resistance. Mechanisms of acquired resistance include 1) the selection of pre-existing subclones with other mutations, 2) the emergence of secondary mutations in the target kinase domain, 3) upregulation of kinases both within the same kinase family and their related kinase families, as well as activation of alternative bypass pathways, 4) epithelial-mesenchymal transition, 5) overexpression of pro-survival Bcl-2 family proteins and 6) drug efflux mechanisms. Currently available methods are to obtain tumor biopsy samples at recurrence or progression if the tumor lesion is accessible to a biopsy and to use the second- and third-generation KIs based on the individual need of each patient. Furthermore, recent computational challenges provide design principles to prevent the development of drug resistance. In conclusion, we provide an overview of the postulated resistance mechanisms and highlight the future direction of computational structure-based design of new potent KIs.
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Heavy Element Accumulation in Aquatic Beetles of the Genus Enochrus (Coleoptera: Hydrophilidae) in Erzurum Province

In the present study, fourteen heavy elements (Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Sr, Pb) accumulation in sediment, water and Enochrus spp. species organs (total body) were evaluated. For this purpose, water, sediment and Enochrus spp. were collected from nine wetland sites in Erzurum province (Turkey).
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Giemsa Staining and Antibody Characterization of Colpodella sp. (Apicomplexa)

Colpodella species are free-living alveolates that possess an apical complex used for attaching to eukaryotic prey protists for ingestion of the cytoplasmic contents of the prey. Colpodella sp. are the closest relatives of the Apicomplexa, a phylum that includes the important human pathogens Plasmodium falciparum, Toxoplasma gondii and Cryptosporidium parvum. In this study, we investigated morphological characteristics of Colpodella (ATCC 50594) in a diprotist culture containing Bodo caudatus as prey in order to identify features differentiating both protists. The level of apical complex protein conservation among free living alveolate relatives of apicomplexans and intracellular apicomplexan pathogens is unknown. Antibodies against proteins of the apical complex in Colpodella sp. are currently unavailable. We performed staining and immunological characterization of Colpodella in a diprotist culture containing B. caudatus to aid routine differentiation of predator and prey in culture. Staining revealed distinguishing morphological features of both protists. The kinetoplast in B.caudatus was identified using Giemsa staining and was used to differentiate B. caudatus from Colpodella sp. trophozoites.
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The Human –Cat Relationship, Myths/Superstitions and its Consequences on Cat Ownership in Maiduguri, Northeastern Nigeria

A survey was designed to determine the human-cat relationship, myths/superstition and its consequences on cat ownership in Maiduguri, Nigeria. Close ended structured questionnaires were administered to 200 households randomly selected from four wards in Maiduguri. The response rate was 98.0%. Out of the 200 households, 196 (98.0%) participated, while 4 (2.0%) did not. Of the 196 households that took part in the survey, 168 (84.0%) owned cats while 28 (14.0%) did not. A total of 310 cats were owned by the 168 participating households. Elderly women owned 55.5% of the cats, while children and young ladies owned 35.0% and 3.5% respectively. Only 1 cat was neutered, while the remaining 309 (99.7%) were intact. The cats were kept for the purpose of companionship and rodent control. All the cats were of non-specific breed and had never been vaccinated against any specific disease(s). Some cat owners in Maiduguri believed in myths/superstitions associated with the domestic house cat. However, it was concluded that households in Maiduguri viewed keeping cats positively but did not provide the expected housing, feeding and medications as practiced in more advanced countries.
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Communist Extremists, Islamic Supremacists, and Narco-Terrorists: A Forensic Sociological Threat Analysis of Radicalization within the Federative Republic of Brazil

This article presents a human terrain analysis of the Islamic radicalization occurring in Latin America and the infiltration of the Al-Qaeda terrorist network into the country of Brazil. The study used sociological investigative research methods conducted in Brazil, extensive ethnographic interviews collected in the major Brazilian cities of Sao Paulo and Rio de Janeiro, and intensive Brazilian Portuguese language immersion. The ethnographic research techniques examined the social, political, religious, and linguistic structures to gain an understanding of how Al-Qaeda operatives have established an operational base in Brazil. The study provides an early warning sociological intelligence assessment of the threat of radical Islam in Latin America.
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Effect of Father Involvement in Infant Feeding on Nutritional Status and Morbidity in Kisumu, Kenya

9060IntroductionObjective: Interventions promoting optimal breastfeeding could prevent 13%, while those promoting optimal complementary feeding could prevent another 6%, of deaths in countries with high mortality rates. This study determined the influence of father’s participation in promoting infant feeding on nutritional status and morbidity patterns in Kisumu East Sub County, Kisumu County.
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A Randomized Double-Blind Placebo Controlled Clinical Trial Evaluating the Effects of an Investigational Study Product on Exercise Induced Muscle Soreness, Markers of Inflammation, Muscle Damage and Exercise Performance in Healthy Males

Gherkin, a pure botanical extract from cucumber is a phytonutrient rich vegetable which may have been shown to have anti-inflammatory and pain relieving properties. The purpose of this randomized double-blind placebo study was to determine the effects of Gherkin (Cuvitus™, Actido®)on exercise performance, markers of inflammation and acute muscle soreness in healthy males.
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An Infant with Liver, Kidney, Skin and Musculoskeletal Abnormalities

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Subacute Facial Nerve Paralysis Following Cyberknife Treatment for Vestibular Schwannoma

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Fixed Pigment Erythema: A Challenge

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Leriche Syndrome: Percutaneous Treatment with Mechanical Thrombectomy: A Case Report

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Introduction to the special issue on ‘Nanostructures by Valve Metal Anodization’

With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.
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Ordered Growth of Anodic Aluminum Oxide in Galvanostatic and Galvanostatic-Potentiostatic Modes

The results are presented of obtaining anodic aluminum oxide with an ordered pore arrangement by employing two anodizing modes - galvanostatic mode and combined (galvanostatic + potentiostatic) mode, at high values of the current density and voltage. Use has been made of an oxalate electrolyte and a complex electrolyte comprising oxalic acid and phosphoric acid. Scanning electron microscopy has been used to investigate the surface morphology of the barrier and porous layers and to determine pore sizes and inter-pore distance.
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Anodic Porous Alumina Array for Cyanine Fluorophore Cy3 Confinement

Self-organized anodic porous alumina films with hexagonal pore lattice have attracted a considerable attention for biological arrays and confinement of various organic probes dyes in solutions. A molecular structure with axial symmetry in bis-heterocyclic indole chains and conjugate system, such as cyanine fluorophore Cy3 dye, was investigated here with respect to its fluorescence when loaded in the anodic alumina pores.
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Anodizing for Design and Function

Two basic reactions occur during the anodizing of aluminum: 1) the aluminum is consumed and 2) an oxide grows. By accepting this statement as true, the anodizing process can be viewed as a corrosion process, and anodizing can be modeled using the Tafel Equation. Anodizing process parameters of electrolyte chemistry and concentration, temperature, aluminum substrate resistance and current density are presented as they relate to the Tafel Equation and how they impact the anodic aluminum oxide structure and properties. Understanding this relationship is consequent in making anodizing an engineering process, one that enables tuning the structure such that it yields distinct characteristics to fulfill design and application requirements.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Analysis of Sweat Simulant Mixtures using Multiplexed Arrays of DNA-Carbon Nanotube Vapor Sensors

Carbon nanotube (NT) based electronic vapor sensors were tested against synthetic sweat solutions, consisting of 13 volatile organic compounds (VOCs) in saline, in order to probe the device ability to analyze and differentiate vapors derived from complex biological samples.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Fabrication of Ordered Arrays of Anodic Aluminum Oxide Pores with Interpore Distance Smaller than the Pitch of Nano-pits formed by Ion Beam Etching

We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication of Vertical Cu2ZnSnS4 Nanowire Arrays by Two-Step Electroplating Method into Anodic Aluminum Oxide Template

Vertical Cu2ZnSnS4 (CZTS) nanowire arrays have been synthesized via two-step electroplating method into anodized aluminum oxide template. For deposition of CZTS nanowires, anodized aluminum oxide (AAO) was used as the growth mask for the growth of the nanowires. AAO templates with hole sizes of 70 nm in diameter were used in the experiments.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Synthesis of BaTiO3 Nanowires via Anodic Aluminum Oxide Template Method Assisted by Vacuum-and-Drop Loading

In this paper, we report on the synthesis of BaTiO3 nanowires via the anodic aluminum oxide template method. To fill in the precursors of BaTiO3 into anodic aluminum oxide templates, the vacuum and drop loading method developed in our previous study was used. Ba(CH3COO)2 (barium acetate) and C12H28O4Ti (tetraisopropyl orthotitanate) were used as Ba and Ti sources, respectively. Anodic aluminum oxide membranes with the through-hole diameter of ~200 nm were used as the template for BaTiO3 nanowires.
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Editorial Board Members Related to m

Jorge Perez

Associate Professor
San Juan Bautista School of Medicine
United States

Jill Slay

Division of Information Technology, Engineering and the Environment
University of South Australia

Ziad N. AL-Dwairi

Fixed and Removable Prosthodontics and Implant Dentistry
Jordan University of Science and Technology

Federico Sesti

Neuroscience and Cell Biology
Robert Wood Johnson Medical School
Rutgers University

Nagendra K. Prasad

Assistant Professor
Division of Hematology and Oncology
Indiana University School of Medicine
United States


Department of Zoology
Faculty of Sciences
Charles University
Czech Republic

Robert R. Redfield

Department of Immunology and Microbiology
University of Maryland
United States

Alireza Heidari

Faculty of Chemistry
California South University (CSU)
United States

Arvind Chhabra

Assistant Professor
Department Of Medicine
University of Connecticut Health Center
United States

Tetsuya Yoshinaga

Institute of Health Biosciences
Tokushima University
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