Recent Articles

Pirfenidone capsules are indicated for the treatment of patients with Idiopathic pulmonary fibrosis. The Bioavailability of two formulations containing pirfenidone 267 mg hard gelatin capsules was compared in a bioequivalence study under fed conditions. The study was single dose, randomized, open label, two-period crossover, with Brazilian healthy subjects, males and nonpregnant females.

Phytophagous insects are dependent on their host plants entirely or part of their life cycle. Host plant supplies food and shelter for their survival. Among the phytophagous insects, aphid is familiar as phloem feeders and act as a career of plant viruses to different agricultural crops. These cause huge economic losses every year in terms of both crop damage and their control measures. Instead of chemical control, it is better to inspect the relationship of aphid with their host plant like selection and adaptation pattern to develop an eco-friendly strategy to manage them.

Due to roles requiring higher levels of emotional management, some case workers report greater job stress and lower well-being. Caffeine consumption and withdrawal can affect well-being and caffeine is consumed more frequently among workers in stressful positions. This project identifies and describes patterns for usage of caffeine, domains of workplace well-being, and correlations between caffeine intake and workplace well-being among case workers.

The concept of an effective cognitive boosting nootropic supplement is gaining traction with consumers, neuroscientists and regulators alike and it is therefore unsurprising that scientifically validated Nootropics are highly prized. New research demonstrates edible crops could be useful sources to mine for new nootropics; plant extracts enriched with an array of cognitive enhancing metabolites. There is merit in investigating these plant species. Metadata has identifies consuming specific fruit and vegetables positively affects cognitive function; therefore these same edible crop plants present as opportunities for developing nootropic formulations. This hypothesis is supported by positive data obtained through clinical testing [e.g. extracts of tomato (Solanum lycopersicum), herbs from the Genus Salvia, cocoa (Theobroma), tea (Camellia sinensisor) and coffee (Coffea Arabica). This review will discuss clinically tested cognitive enhancers derived from edible crop species and discuss their use alongside other classes of nootropics.

Amyloidosis involving the vascular musculoskeletal system is rare and currently, there is no standard treatment protocol for the treatment of skeletal muscle AL amyloidosis associated with vascular myopathies. Furthermore, the data on the efficacy and safety of autologous stem cell transplant is unclear. In this rare case, a biopsy-proven diagnosis of AL type amyloidosis with an unusual presentation of proximal muscle weakness significantly improved with high dose melphalan followed by autologous stem cell transplantation. The patient achieved and maintained remission for a year post-transplant

Infection with Helicobacter pylori(H. pylori) is implicated in iron and vitamin B12 deficiencies without any etiologies. Our prospective study conducted at the Teaching Hospital Yalgado OUEDRAOGO at OUAGADOUGOU (BURKINA FASO) aimed to find a link between H. pyloriinfection and anemia in our context. Patients and Methods:Were selected, patients with iron deficien

Spot blotch of wheat caused by Bipolaris sorokiniana is a problematic biotic constraint that causes 15-80% yield abatement in the Indian subcontinent and other parts of the world

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are markers for screening previous alcohol consumption and indicating recent drinking in cases of suspicion of driving under the influence of alcohol.

Plastics play an important role in modern society and are used daily in diverse applications due to their low cost, ease of manufacturing and attractive qualities

Weight loss is an efficient therapy for obese polycystic ovary syndrome (PCOS) patients. Here we evaluate the effect of dietary weight reduction on clinical performance in obese PCOS patients. Medical records of fifty obese PCOS patients (age 27 ± 5 years) who had calorie-controlled dietary intervention were reviewed. The patients had a 1200-kcal/day diet until ovulation or for up to three months. Changes in body weight, body mass index (BMI), blood pressure, menstruation, acne, and hirsutusm, serum levels of endocrine hormones and adipocytokines, glucolipid metabolism index and insulin resistance were assessed. Menstrual cycle, ovulation andrelapse in the following six months were also reviewed. All patients had menstrual disorder, 43 had acne, and 26 were hirsute. After weight loss, the BMI decreased from 27.89 ± 3.06 to 25.70 ± 2.42 kg/m2 (p < 0.001). Acne and hirsutusm was improved in 39 and 14 patients, respectively. Regular menstruation was restored in 26 patients and lasted for 3.12 months on average. Endocrine hormones levels, adipocytokines levels, glucolipid metabolism and insulin resistance were shifted toward balance. Weight relapse was seen in 11 patients. No side effects occurred. Dietary intervention in obese PCOS patients can improve relevant clinical problems but weight relapse is an issue

The use of gonadotropic stimulation in assisted reproductive technology programs increases the risk of developing the ovarian hyperstimulation syndrome (OHSS), which is considered as a loss of control over the ongoing ovarian stimulation. The severe forms of OHSS lead to the severe complications that threaten the patient’s life.

26 women with HMB and scarred uterus were included in the study. Data regarding procedure completion, complications, hospital stay, success rate and failure of procedure necessitating hysterectomy was obtained. The majority of the patients had one C/S, 5 had two, one had 3 and two had 4 previous C/S scars. The procedure was completed in 84% of cases. Success rate was 68% (15/22) in the scarred uterus group and 32% (31.8%) (7/22) needed hysterectomy due to continuing heavy periods or pain. One woman in the scarred uterus group had uterine perforation (3.8%) needing overnight admission, all the rest of cases were done as a day procedure. A third (7/22)(32%) of women required a hysterectomy for persistent heavy bleeding or pelvic pain, all were with previous one C/S. The histology of the removed uterus confirmed leiomyomas with or without adenomyosis in all the cases explaining the possible cause of failed Novasure ablation.

Sickle cell disease (SCD) is estimated to affect approximately 100,000 Americans. Children and adolescents with chronic medical conditions like SCD require comprehensive care that addresses both medical and psychosocial needs to better control their disease and ultimately maximize function at home, school and the community. The purpose of this quality improvement project was to host a symposium to provide sickle cell disease education and increase awareness of sickle cell disease to patients, families, and the surrounding community.

Despite persistently high rates of obesity among American children and adults, the complex interplay between behavior, genetics and weight outcomes is not well understood.

Charles Bonnet syndrome (CBS) comprises of complex visual hallucinations secondary to visual impairment in the presence of preserved cognition. Age related macular degeneration and other factors causing visual deterioration lead to visual hallucinations in 10-15% of patients. Sensory deprivation and social isolation are risk factors for development of CBS. The distressing hallucinations are underreported by patients and to date there are no robust evidence based guidelines to manage these hallucinations. Since visual hallucinations are associated with multiple psychiatric disorders as well, these patients are often referred to mental health providers. Here, we present the case of CBS development after macular degeneration. Rapid and sustained resolution of visual hallucinations and associated distress was observed with low dose Risperidone.

Imitation is considered as a platform for interdisciplinary studies where social sciences, cognitive psychology, neurobiology and neurocybernetics interact, as well as clinical psychology. It is often used to explore various and several scientific fields but few works have investigated a series of linked successive motor actions. The current work aimed to study and expand the findings regarding which information subjects of different populations selected and included for reproducing demonstrated model ’actions. 120 children of 6 age groups divided between 3 years and 8 years, associated to autistic and deficient children were tested in this present study. This developmental scale completed, should provide a baseline for understanding in what type of constraints the autistic child would be specifically deficient in the management of his imitation. The comparison with mentally deficient children also seemed indispensable. The children’s imitative responses were videotaped, coded in dichotomy data, and then put into percentage. Our expected goal is to characterize the traits of autistic motor skills in reference to normal and mentally deficient development.

Objective: An indirect torque loss evaluation between the slot height and wire dimensions in different ceramic conventional and self-ligating brackets manufacturers. Material and Methods: 30 slot heights of five upper right incisors from 04 commercially available bracket systems were analyzed using a profile projector and 40 stainless steel wires from 04 different manufacturers (width, height and the edge bevel) were measured with a digital micrometer, and a vision-measuring machine. A mathematical formula was used to compare the results of the actual torque loss values versus the theoretical. Results: all brackets were oversized and varied from 0.598 mm (the highest mean) to 0.566 mm (the lowest mean).

Peter A. Levine, Ph.D. has spent 45 years studying and treating stress and trauma. Levine received his PhD. in medical biophysics from the University of California at Berkeley, and also holds a doctorate in psychology from International University (sounds true, 2019)

The number of bariatric procedures being performed worldwide has increased markedly over the past two decades and this has led to revisional bariatric surgery being increasingly performed.

Culture characteristics, routine staining for light microscopy and feeding behavior of Voromonas pontica Cavalier-Smith (American Type Culture Collection, ATCC 50640), a predatory free-living marine colpodellid, was investigated