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Stimulation of IL-16 Release by Cells Exposed to HIV Virion Proteins

The pathogenesis and immune response to a chronic viral infection is multifaceted especially for HIV infection. The effect of HIV on the systemic immunoenvironment of the infected individual is profound and triggered by multiple stimuli. While replication competent viral infection induces a large spectrum of immune responses, such as cytokine release, we focused on what happens when cells are exposed to replication incompetent virions and their components.
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A Preliminary Evaluation Study to Determine the Effectiveness of Infra-Red Photography for the Rapid Visualisation of Gun Shot Residue on Fabric

Infrared (IR) photography has been shown to be a proficient technique for the examination of documents, blood traces and ageing of skin injuries. However, its application in relation to the visualisation of latent Gunshot Residue (GSR) deposits has, until now, been significantly under researched. This paper evaluates the effectiveness of IR photography as a rapid technique for GSR visualisation on different fabric types. The Attestor Forensics Scene View BV800 viewing system was used to visualise GSR deposits, produced by a Glock 17 9x19mm and 9mm Luger ammunition, on four different fabric types and at three firing distances of 50mm, 200mm and 1000mm. The results demonstrate that IR photography can produce comparable results to other GSR visualisation techniques, without the limitations of disturbing the sample’s structure or being obstructed by certain material types.
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Occurrences of Dairy Calf Mortality and Morbidity and the Associated Risk Factors in Sululta and its Environs, Central Ethiopia

Calf morbidity and mortality are important causes of economic losses on dairy farms worldwide. A cross-sectional study and clinical observation was conducted from November 2016 to April 2017 with the objective of determining calf morbidity and mortality and to investigate the potential risk factors for mortality and morbidity in Sululta and its environs. A total of 312 respondents engaged in market oriented small holder dairying were interviewed using a structured questionnaire survey about their farm and calf management practices and major calf health problems encountered and diseases that causes mortality. The overall magnitude of morbidity and mortality of calves were 31.0% and 58.37%, respectively. The major calf diseases found were diarrhea (69.34%), pneumonia (16.54%), liver fluke (2.4%), bloat (2.0%), joint ill (2.4%) and other cases (8.04%). Risk factors such as weaning age, breed and awareness of colostrums, feeding of calf and overall farm management were included. In this study 80.3% of calf mortality occurs under age 3 month and 19.42% is above 3 month. Based on laboratory examination, Salmonella and E.coli were detected from diarrheic calves. Salmonella found at rate of 2/29 (3.6%) and E.coli found at only genus level. In conclusion, the magnitude of calf morbidity and mortality found in this study were much higher than economically tolerable level and could greatly affect the productivity of the dairy farms through mainly decreasing the availability of replacement stock and production of milk. It is therefore, suggested that implementation of improved calf and farm management practices and proper environmental protection in the study areas would significantly reduce calf mortality and morbidity.
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Cattle Ticks and Tick Borne Haemoparasite Species Identification and Associated Risk Factors in Two Districts of West Arsi Zone, Ethiopia

Different tick species and tick-borne diseases of cattle are present in Ethiopia and they induce huge production loss in livestock industry by creating serious animal health problems. The present study was conducted from November 2017 to April 2018 in Arsi Negele and Asasa districts of West Arsi Zone, Oromia National Regional State, Ethiopia. A cross sectional study design and purposive sampling technique were employed to select 384 study animals so as to identify ticks species and tick-haemoparasite species and also to identify risk factors that affect the prevalence and association of tick born diseases. Tick and haemoparasite identification were carried out by using drect stereomicroscopic and direct thin blood examination. The study identified two tick genera and four tick species. The tick species encountered were Rhipicephalus decoloratus (51.6%) Ambylomma variegatum (46.1%) Ambylomma gemma (20.1%) and Rhipicephalus evertsi evertsi (1.2%). Out of all 384 cattle examined for the presence of tick-born haemoparasites 11.4% (n=44) of them were positive. From this 6.2%, 3.6 %, 1.3% and 0.8% of them were positive for Anaplasma marginale, Babesia bigemina, Babesia bovis and Anaplasma marginale, respectively. Two cattle (0.5%) were found positive for both Anaplasma marginale and Babesia bigemina. The highest prevalence of total tick born haemoparasites (57.1%) was occurred in A. Variegatum, A. gemma and R. decoloratus mixed infestations. In conclusion ticks and tick born haemoparasitic infections were common problems in the study area. Thus, awareness creation for farmers about the impacts of ticks and tick born diseases on livestock production and productivity and also applying appropriate and timely strategic tick control methods by veterinary service providers were advisable.
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Epidemiological Profile of Congenital Cardiopathy Neonatal Revelation in Tehran

Congenital heart disease is the most common congenital disorder in newborns represents a major cause of perinatal death. The prevalence of these malformations is still unrecognized in Tunisia because of the lack of a national register. The aim of this study was describe the epidemiological and clinical aspects of the heart diseases with neonatal diagnosis in Tunisia.
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Immunohistochemical Localization of LH Receptors in Canine Splenic Hemangiosarcoma

Gonad removal has been implicated as a risk factor for the development of canine hemangiosarcoma. With gonad removal, there is a loss of negative feedback to the anterior pituitary, resulting in persistently elevated concentrations of luteinizing hormone (LH). LH receptors can be found in gonadal and extragonadal tissues, including the bladder and skin. The aim of this study was to investigate if LH receptors were expressed in canine splenic hemangiosarcoma. Splenic tumor samples submitted to the Oregon State Veterinary Diagnostic Laboratory from referring veterinarians were with routine immunohistochemical methods. In addition, survival time following hemangiosarcoma diagnosis was obtained from the referring veterinarians. Five of the eight splenic hemangiosarcomas (62.5 %) were positive for LH receptor expression. LH receptor cellular localization in splenic hemangiosarcoma was cytoplasmic and granular, similar to the positive control canine skin sections (Figure 1C). There was no positive staining in the negative controls. LH receptor is expressed in a proportion of HSAs but further study need to be done to assess the significance of this finding.
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Adynamic Donor Ureter: A Case Report with Review of the Literature

We report a unique case of a male recipient who received a zero mismatch kidney with mild anatomical anomalies from his sister. This right kidney was malrotated, had an extra renal pelvis with moderately dilated ureter up to the iliac artery bifurcation. Immediate graft function was achieved on reperfusion, and the recipient was discharged on day 7 with a serum creatinine (SC) of 1.8mg/dl. The DJ stent was removed after 6 weeks, with a rapid increase in SC to 3.5mg/dl, and ultrasound showed mild hydronephrosis with delayed excretion on nuclear imaging. Mechanical obstruction was excluded by retrograde pyelography, and a 5F DJ stent was placed across the ureterovesical anastomosis with an immediate decrease in SC. The case is presented in detail and discussed in the light of the current literature.
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Nigeria’s E-Waste Management: Extended Producer Responsibility and Informal Sector Inclusion

This paper explores the emerging role of the private sector and public-private partnerships for e-waste management in the developing world. We use a combination of two conceptual frameworks, the triple bottom line approach and the sustainable livelihoods approach, to analyze the case study of the Extended Producer Responsibility (EPR) programme in Nigeria, which was launched in 2016. The sustainable livelihoods approach has been adopted in international development for over two decades, but so far it has not been applied for inclusion of informal sector workers in e-waste. Our findings illustrate how the financial and environmental bottom lines have already received considerable attention during the development of the Nigerian EPR programme, but that the social elements, in particular informal sector inclusion, have received less attention. Consequently, based on proven practices of the sustainable livelihoods approach, this paper identifies opportunities and provides recommendations as to how the international and national private sector players and government agencies involved in Nigeria’s e-waste EPR programme can establish a social engagement model to support inclusion of the informal sector. This model would not only help meet the financial and environmental bottom lines, but also address the social bottom line to improve livelihood outcomes for informal e-waste recyclers.
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His Bundle Pacing: Short Review of Literature and Technical Aspects

History of pacing has evolved from the primitive state of temporary transvenous pacing by a large fixed machine to leadless modern technology. The pacing site has also been changed from traditional right ventricular apex to various other sites. The concept behind such experiment was due to several complications in the long term from traditional Right Ventricular Apical Pacing (RVAP). The His Bundle pacing results in conduction and contraction similar to and more often called physiological pacing. This mini-review describes the short history of the evolution of the concept of His Bundle pacing and its technical aspects of successful implantation.
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Early Spondyloarthritis Presenting as Premenopausal Osteoporosis and Multiple Vertebral Fractures: A Case Report

We report a 30-year-old woman who presented during pregnancy with mechanical type backache due to non-traumatic multiple vertebral fractures. In-depth the assessment revealed multiple risk factors for osteoporosis, including adolescent steroid use for asthma, prolonged breastfeeding, and vitamin D deficiency. She also had persistently elevated inflammatory markers with radiological evidence of early inflammatory Sacro-ileitis. The rheumatoid factor and HLA B27 were negative. She was successfully managed with NSAIDS, zoledronic acid, and calcium supplementation. This is an example of early inflammatory arthritis in the background of multiple risk factors causing osteoporosis severe enough to cause fragility fractures. This signifies the importance of screening for multiple risk factors in pre-menopausal osteoporosis even in the presence of one or two identified risk factors.
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Evaluation of Nitrogen, Phosphorus and Potassium Nano-Fertilizers on Yield, Yield Components and Fiber Properties of Egyptian Cotton (Gossypium Barbadense L.)

Field experiments were carried out in Agricultural and Experimental Research Station in years 2016 and 2017 to evaluate NPK nano- fertilizers application, times, methods and rates on yield and fi ber properties of Egyptian cotton (Giza, 90). Th e experiment was laid out in a split-split-plot based on Randomized Complete Block Design with four replications.
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Spatial and Temporal Distribution of Rainfall and Rainy Days over the Goa State

Planning for water resources development in a basin or over a region requires careful assessment of the available water resources and reasonable needs of the basin/region in foreseeable future for various purposes such as drinking water, irrigation, hydro-power, navigation, etc. There are several ongoing river water disputes between different states of India, especially in the peninsular region due to decrease in rainfall during the past 15 years or so. The sharing of water of the Mondovi River is a cause of dispute between the Governments of Maharashtra, Karnataka and Goa states. An attempt has therefore, been made to study the characteristics of rainfall distribution over the Goa state using daily and monthly rainfall data. The study mostly comprises of spatial distribution of rainfall, seasonal and annual rainfall trend, relationship between rainfall and rainy days, mean daily rainfall intensity (MDI) and yearly variation of rainfall as well. The results of this study would form basis for various studies in administrating fresh water sources, projecting the investments to prevent the urban areas from the flood and proper planning of the agricultural activities in the State.
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The Incidence and Durability of Compensatory Hypertrophy in Pediatric Patients with Solitary Kidneys

To evaluate the incidence and durability of compensatory hypertrophy with solitary kidneys in the setting of those with multicystic dysplastic kidney or Wilms tumor status post nephrectomy. We conducted a retrospective cohort study of patients with multicystic dysplastic kidney (MCDK) and Wilms tumor (WT). MCDK patients were verified by sonographic findings prenatally. WT patients entered our study at time of nephrectomy. We compared the natural history of hypertrophy between the two cohorts via renal length measurement. We performed linear regression to predict creatinine clearance from renal length after adjusting for age and cohort status (MCDK v. WT).
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Novel Multi-Functional Dental Cement for Enamel Remineralization and AntiCariogenic Bacteria Activity

This experimental study evaluated the release of fluoride and several minerals related to remineralization from novel functional cement, apatite ionomer cement (AIC), and its anti-bacterial properties compared with glass ionomer cement (GIC) and surface pre-reacted glass-ionomer filler containing composite resin (giomer). Conventional GIC (Fuji III, GC Co., Tokyo, Japan) was used as the control and fundamental materials. In the AIC powder, 28% wt of GIC powder was replaced with spherical-shaped hydroxyapatite powder. The giomer, BeautiSealant (Shofu Co., Kyoto, Japan), was used as a positive control. Each specimen was immersed in deionized water and analyzed by inductively coupled plasma atomic emission spectrometry (for Al, Si, P, Ca and Sr) and a fluoride-selective electrode. Antibacterial activity against Streptococccus mutans was evaluated using the adenosine-5’-triphosphate luminescence method. Concentrations of released ions from AIC specimens were significantly higher than those from GIC and giomer specimens. Regarding antibacterial activity, luminescence intensity of the AIC group was significantly lower than that of the control and giomer groups. It was concluded that AIC could be a most suitable material for pit and fissure sealant for enamel remineralization and anti-cariogenic and -bacterial activity.
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Dysautonomia after Spinal Cord Injury: A Clinical Case

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Introduction to the special issue on ‘Nanostructures by Valve Metal Anodization’

With this special issue of JMSN we are pleased to present significant contributions to a fascinating topic in the field of materials nanostructing, which is the anodization of valve metals. By this treatment porous oxides of controlled geometry can be grown on the respective metal surfaces. To date, aluminum (Al) has been used most often, as confirmed in this special issue where nine out of ten contributions deals with its anodization.
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Recent Developments in Human Odor Detection Technologies

Human odor detection technologies have drawn attention due to the wide possibility of potential applications they open up in areas such as biometrics, criminal investigation and forensics, search for survivors under rubble, and security checkpoint screening. Gas chromatography/mass spectrometry (GC/MS) has been the most successful and powerful analytical approach developed to date for human odor analysis, and hundreds of human odorants have been identified using this tool.
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Electronic-nose Applications in Forensic Science and for Analysis of Volatile Biomarkers in the Human Breath

The application of electronic-nose (E-nose) technologies in forensic science is a recent new development following a long history of progress in the development of diverse applications in the related biomedical and pharmaceutical fields. Data from forensic analyses must satisfy the needs and requirements of both the scientific and legal communities. The type of data collected from electronic-nose devices provides a means of identifying specific types of information about the chemical nature of evidentiary objects and samples under investigation using aroma signature profiles of complex gaseous mixtures containing volatile organic compounds (VOCs) released from manufactured products and parts of the human body. E-nose analyses also provide useful qualitative information about the physicochemical characteristics and metabolic conditions of human subjects without the need for time-consuming analyses to identify all chemical components in human-derived volatile mixtures.
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Characteristic Human Scent Compounds Trapped on Natural and Synthetic Fabrics as analyzed by SPME-GC/MS

The collection of human odor volatiles is of interest to forensic applications as a path to investigate canine scent discriminations in legal investigations. A study using a selected array of previously identified human odor compounds has been conducted to determine the retention and release capabilities of five (5) natural and synthetic fabric types, cotton (mercerized fabric and gauze matrix), polyester, rayon and wool.
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The Effects of the Film Thickness and Roughness in the Anodization Process of Very Thin Aluminum Films

The anodization of aluminum foils having micrometer thickness is a common process and results in hexagonally self-ordered alumina membranes. However, anodic aluminum oxide (AAO) membranes fabricated from nanometer-thin films present new challenges to the anodization process, since aluminum films adheres poorly on supporting substrates and the smoothness of the film is highly related to the kind of substrate.
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Anodic Oxidation of Titanium in Sulphuric Acid and Phosphoric Acid Electrolytes

Anodisation of pure titanium has been carried out in sulphuric and in phosphoric acid solutions at potentials ranging from 50 to 150V. The SEM and AFM morphological analysis indicates that, within this potential range, oxidation in sulphuric acid solution produces better developed mesoporous oxide layers.
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Fabrication of Ordered Arrays of Anodic Aluminum Oxide Pores with Interpore Distance Smaller than the Pitch of Nano-pits formed by Ion Beam Etching

We investigated a method for preparation of ordered nanopore arrays with the interpore distance of 60 nm by guided self-organization of anodic aluminum oxide with a prepatterned array of pits in the starting Al film.
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Preparation of Large Area Anodic Alumina Membranes and their Application to Thin Film Fuel Cell

The design of an electrochemical reactor for the preparation of self-supported comparatively thin (up to 10 μm) and large area (up to 50 cm2) anodic alumina membranes is described allowing growth of porous alumina at high applied potential (up to 150 V) without burning.
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Fabrication and Luminescence of Anodic Alumina with Incorporated Vanadyl Citrate Chelate Anions

Anodic aluminum oxide doped with vanadyl citrate chelate complex anions was formed by a two-step self-organized anodization in 2 wt. % sulfuric acid containing 0.04 M V2O5 and 0.08 M citric acid at voltage range 13-23 V, and at 0 and 15 oC. The combination of two temperatures and at least four voltages (depending on the applied temperature) was applied as the operating conditions of anodization.
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Editorial Board Members Related to SP

ANNABELLA VITALONE

Assistant Professor
Department of Physiology and Pharmacology
University of Rome
Itlay

Ana Rita Ramalho Figueiras

Faculty of Pharmacy
University of Coimbra
Portugal

Scott Asbill

Professor
Department of pharmaceutics
Presbyterian College School of Pharmacy
United States

Helena Nunes Cabaco

Research associate
Institute of Molecular Medicine
Faculty of Medicine
University of Lisbon
Portugal

Saul Yedgar

Professor
Department of Biochemistry
Hebrew University
Israel

Mirosław Kwiatkowski

AGH University of Science and Technology
Faculty of Energy and Fuels
Poland

Nelson Pérez Guerra

Professor
Department of Biochemistry
University of Vigo
Spain

Shubiao Wu

Associate Professor
Aarhus Institute of Advanced Studies
Aarhus University
Denmark

Syed Zulkarnain Syed Idrus

Senior Lecturer
School of Human Development and Technocommunication
University Malaysia Perlis
Malaysia

Salim A. Hamadi

Professor
Department of Pharmacology and Biomedical Sciences
Petra University
Jordan
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